Psoriasin (S100A7): A putative urinary marker for the follow‐up of patients with bladder squamous cell carcinomas

Psoriasin (S100A7): A putative urinary marker for the follow‐up of patients with bladder squamous cell carcinomas
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银屑病素 (S100A7):用于膀胱鳞状细胞癌患者随访的假定尿液标记物

DOI:
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发表时间:
1999
期刊:
影响因子:
2.9
通讯作者:
J. Celis
J. Celis
中科院分区:
生物学3区
文献类型:
--
作者:
M. Oestergaard;H. Wolf;T. Oerntoft;J. Celis

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为了寻找释放到尿液中的膀胱鳞状细胞癌标志物,使用最先进的蛋白质组学技术对新鲜肿瘤、其分泌蛋白以及患者尿液的蛋白质谱进行了盲法和系统性分析。我们回顾了关于假定的标志物银屑病(S100A7)的数据,单独或与其他生物标志物结合,可能对这些肿瘤患者的无创随访有价值。
To search for bladder squamous cell carcinoma markers that are released to the urine a blind and systematic analysis of the protein profiles of fresh tumors, their secreted proteins, as well as the patient's urine was carried out using state‐of‐the‐art proteomic technology. We review the data concering the putative marker psoriasin (S100A7), which, alone or in combination with other biomarkers, may be valuable for the noninvasive follow‐up of patients bearing these tumors.