UTGB toolkit for personalized genome browsers
UTGB toolkit for personalized genome browsers
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DOI：
10.1093/bioinformatics/btp350
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发表时间：
2009-08-01
期刊：
影响因子：
5.8
通讯作者：
Morishita, Shinichi
中科院分区：
文献类型：
--
作者：
Saito, Taro L.;Yoshimura, Jun;Morishita, Shinichi
高通量DNA测序仪的出现加快了收集大量基因组信息的步伐，每周可以产生数十亿个核苷酸。就单位时间内核苷酸的数量而言，这一进步比传统的桑格测序仪提高了两个数量级，即使是小团队的研究人员也可以在相当短的时间内获得大量的基因组数据。因此，迫切需要开发个性化的基因组浏览器来分析这些大量的本地存储数据。UTGB（东京大学基因组浏览器）工具包旨在满足基因组浏览器个性化的三个主要要求：以最小的努力轻松安装系统，浏览本地存储的数据以及根据个人需求量身定制的web界面的快速交互设计。UTGB Toolkit是在开源许可下授权的。
The advent of high-throughput DNA sequencers has increased the pace of collecting enormous amounts of genomic information, yielding billions of nucleotides on a weekly basis. This advance represents an improvement of two orders of magnitude over traditional Sanger sequencers in terms of the number of nucleotides per unit time, allowing even small groups of researchers to obtain huge volumes of genomic data over fairly short period. Consequently, a pressing need exists for the development of personalized genome browsers for analyzing these immense amounts of locally stored data. The UTGB (University of Tokyo Genome Browser) Toolkit is designed to meet three major requirements for personalization of genome browsers: easy installation of the system with minimum efforts, browsing locally stored data and rapid interactive design of web interfaces tailored to individual needs. The UTGB Toolkit is licensed under an open source license.