The significance of ophthalmological symptoms in idiopathic blepharospasm
The significance of ophthalmological symptoms in idiopathic blepharospasm
复制标题
特发性眼睑痉挛眼科症状的意义
作者：
J. Elston;Marsden Cd;F. Grandas;N. Quinn
本文回顾了272例特发性眼睑痉挛患者，以确定局部眼病在其疾病中的作用。大多数患者（57%）在发病时有眼睛干燥、沙砾、刺激或畏光等症状，表明眼睑或眼表有疾病。272例患者中有170例在发病时进行了详细的眼科检查；这些患者中有64%有眼部症状，40%有明显的眼表或眼睑病理。这种病理通常是双侧的，慢性的，对局部治疗有抵抗力。在这些患者中，眼睑痉挛的发展经历了很长的潜伏期，通常长达多年。单侧病理是急性的，通常对局部治疗反应良好，但通常在六个月内发展为双侧眼睑痉挛。在所有272名患者中，在发病时没有眼部症状的患者很少在发病后出现眼部症状；如果有，也没有异常迹象。数据表明，眼科疾病可能会引发特发性眼睑痉挛在相当大的比例的情况下，倾向于发展这种情况。
Two hundred and seventy-two patients with idiopathic blepharospasm were reviewed to establish the role of local eye disease in their illness. The majority of patients (57%) had symptoms at the onset of their illness such as dryness of the eyes, grittiness, irritation or photophobia suggesting eye lid or ocular surface disease. Detailed ophthalmological examination at the time of presentation had been carried out in 170 of the 272 cases; 64% of these patients had ocular symptoms, and 40% had demonstrable ocular surface or eye lid pathology. Such pathology was usually bilateral, chronic and resistant to local treatment. Blepharospasm developed in these patients after a long latent period, often of many years. Unilateral pathology was acute, normally responded well to local treatment, but was followed by the development of bilateral blepharospasm usually within six months. Amongst all 272 patients, those without ocular symptoms at presentation rarely developed them subsequently; if they did, there were no abnormal signs.The data suggest that ophthalmological disorders may trigger idiopathic blepharospasm in a substantial proportion of cases predisposed to develop this condition.