Granular cell peripheral odontogenic fibroma.
Granular cell peripheral odontogenic fibroma.
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颗粒细胞周围牙源性纤维瘤。
DOI：
10.1111/j.1600-0714.1976.tb01778.x
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发表时间：
1976
期刊：
影响因子：
--
通讯作者：
M. Shear
中科院分区：
文献类型：
--
作者：
J. Lownie;M. Altini;M. Shear
报告一例周围牙源性纤维瘤，其包含大颗粒细胞聚集。这些颗粒细胞类似于先前描述的颗粒细胞肌母细胞瘤、先天性膝脓肿和颗粒细胞成釉纤维瘤。在周围牙源性纤维瘤中，经常观察到以双链方式覆盖的牙龈上皮基底层的深度延伸。这些链与肿瘤本身的链非常相似。在此基础上，由于在其他颌骨病变中也可以看到类似的基底细胞延长，因此可以假设残余的外充质影响可能以类似于早期胚胎牙齿发育期间发生的方式诱导基底细胞增殖。这可能是外周牙源性纤维瘤中牙源性上皮链的组织发生。
A case of a peripheral odontogenic fibroma which contained aggregates of large granular cells is reported. These granular cells are similar to those previously described in the granular cell myoblastoma, congenital epulis and the granular cell ameloblastic fibroma. Deep extensions of the basal layer of overlying gingival epithelium, in double-strand fashion, are frequently observed in peripheral odontogenic fibromas. These strands closely resemble those seen in the tumor itself. On this basis, and as similar basal cell prolongations are seen in otherjaw lesions, it is postulated that residual ectomesenchymal influence may be responsible for inducing the basal cell proliferations in a similar manner to that which occurs during early embryonic dental development. This, it is suggested, might possibly be the histogenesis of the odontogenic epithelial strands in the peripheral odontogenic fibroma.