Coarse-Graining the Fluid Flow around a Human Sperm
Coarse-Graining the Fluid Flow around a Human Sperm
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DOI：
10.1103/physrevlett.118.124501
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发表时间：
2017-03-23
影响因子：
8.6
通讯作者：
Kirkman-Brown, Jackson
中科院分区：
文献类型：
--
作者：
Ishimoto, Kenta;Gadelha, Hermes;Kirkman-Brown, Jackson
鞭毛节拍是从人类精子数字成像显微镜中提取的，并通过边界元模拟来确定细胞周围的流动及其轨迹。将预测的细胞轨迹与观测结果进行比较表明，模拟可以在定性的水平上预测精细的精子动力学。流场也被观察到归结为正则化的Stokes流动奇点的随时间变化的总和，在前导阶处由一个闪光力三元组近似。这种规则化的奇点分解可能被用来将细胞水平的细节提升到人类精子运动的群体模型中。
The flagellar beat is extracted from human sperm digital imaging microscopy and used to determine the flow around the cell and its trajectory, via boundary element simulation. Comparison of the predicted cell trajectory with observation demonstrates that simulation can predict fine-scale sperm dynamics at the qualitative level. The flow field is also observed to reduce to a time-dependent summation of regularized Stokes flow singularities, approximated at leading order by a blinking force triplet. Such regularized singularity decompositions may be used to upscale cell level detail into population models of human sperm motility.