Combining Indoor Residual Spraying and Insecticide-Treated Net Interventions
Combining Indoor Residual Spraying and Insecticide-Treated Net Interventions
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DOI：
10.4269/ajtmh.2009.81.519
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发表时间：
2009-09-01
影响因子：
3.3
通讯作者：
Coleman, Michael
中科院分区：
文献类型：
--
作者：
Kleinschmidt, Immo;Schwabe, Christopher;Coleman, Michael
扩大疟疾：结合室内滞留喷洒(IRS)和长效杀虫蚊帐(LLIN)进行控制是否加强了对人口的保护？本文介绍了赤道几内亚比奥科和莫桑比克赞比西亚最近的文献检索和家庭调查的结果。在之前的八项研究中，有五项报告称，与仅使用一种干预措施相比，接受两种干预措施保护的患者感染风险降低。比奥科和赞比西亚州的调查显示，与单独使用IRS相比，IRS与蚊帐结合使用具有保护作用的有力证据(比奥科的优势比[OR]=0.71，95%可信区间[CI]=0.59-0.86，赞比西亚州的OR=0.63，95%CI 0.50-0.79)。在Bioko和赞比西亚州，两种干预措施联合使用的OR值分别为0.46(95%CI=0.76~0.81)和0.34(95%CI=0.21~0.56)。尽管不能排除混淆的影响，但这些结果鼓励人们，将IRS和LLIN结合起来的额外资源是合理的。
Does scaling up of malaria: control by combining indoor residual spraying (IRS) and long-lasting insecticidal nets (LLIN) enhance protection to populations? Results from a literature search and from recent household surveys in Bioko, Equatorial Guinea, and Zambezia, Mozambique are presented. Five out of eight previous studies reported a reduced risk of infection in those protected by both interventions compared with one intervention alone. Surveys in Bioko and Zambezia showed strong evidence of a protective effect of IRS combined with nets relative to IRS alone (odds ratio [OR] = 0.71, 95% confidence interval [CI] = 0.59-0.86 for Bioko, and OR = 0.63,95% CI 0.50-0.79, for Zambezia). The effect of both interventions combined, compared with those who had neither, was OR 0.46, (95% CI = 0.76-0.81) in Bioko and 0.34 (95% CI = 0.21-0.56) in Zambezia. Although the effects of confounding cannot be excluded, these results provide encouragement that the additional resources for combining IRS and LLIN are justified.