Prevalence and incidence of hepatitis C virus infection among young adult injection drug users
Prevalence and incidence of hepatitis C virus infection among young adult injection drug users
复制标题
DOI：
10.1097/00042560-199802001-00004
复制
发表时间：
1998-07-01
期刊：
影响因子：
--
通讯作者：
Vlahov, D
中科院分区：
文献类型：
--
作者：
Garfein, RS;Doherty, MC;Vlahov, D
通过社区外展，年轻成人注射吸毒者（IDUs）被纳入了一项关于丙型肝炎病毒（HCV）感染流行率、发病率和危险因素的前瞻性研究。在半年一次的访谈中收集了性行为和注射行为的人口统计数据和信息，并使用第二代抗体测定法评估HCV感染。在229名参与者中，86名（37.6%）基线时hcv血清阳性。在通过逻辑回归调整注射频率和持续时间后，HCV血清阳性率与在过去6个月内至少重复使用一次注射器（优势比[OR] = 3.81, 95%可信区间[CI] 1.39-11.00）、与大于或等于5岁的人（OR = 2.99; 95% CI, 1.43-6.23）或单独（OR = 4.02; 95% CI, 1.12-14.43）与与他人一起注射的情况独立相关
Through community-based outreach, young adult injection drug users (IDUs) were enrolled in a prospective study of the prevalence, incidence, and risk factors for hepatitis C virus (HCV) infection. Demographics and information on sexual and injecting practices were collected during semiannual interviews, and HCV infection was evaluated using a second-generation antibody assay. Of the 229 participants, 86 (37.6%) were HCV-seropositive at baseline. After adjusting for injecting frequency and duration by logistic regression, HCV seroprevalence was independently associated with reusing syringes at least once in the past 6 months (odds ratio [OR] = 3.81, 95% confidence interval [CI] 1.39-11.00), injecting the first time with someone greater than or equal to 5 years older (OR = 2.99; 95% CI, 1.43-6.23) or alone (OR = 4.02; 95% CI, 1.12-14.43) versus with someone