OSTEOCLASTS DERIVED FROM HEMATOPOIETIC STEM-CELLS
OSTEOCLASTS DERIVED FROM HEMATOPOIETIC STEM-CELLS
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DOI:
10.1038/283669a0
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发表时间:
1980-01-01
期刊:
影响因子:
64.8
通讯作者:
TOWNSEND, KMS
中科院分区:
文献类型:
--
作者:
ASH, P;LOUTIT, JF;TOWNSEND, KMS
The origins of the multinucleated osteoclast have been controversial, with osteogenic precursors1and haematopoietic stem cells2as candidates. Recent evidence for the latter is persuasive but circumstantial. We report here direct evidence obtained in radiation chimaeras from a natural cytoplasmic cell marker transmitted by the donated haematopoietic stem cell.