REACTION OF 1-BENZYL-1H-TRIAZOLE-4,5-DICARBOXALDEHYDE WITH CYCLIC-KETONES
REACTION OF 1-BENZYL-1H-TRIAZOLE-4,5-DICARBOXALDEHYDE WITH CYCLIC-KETONES
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DOI：
10.1021/je00047a039
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发表时间：
1987-01-01
期刊：
影响因子：
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通讯作者：
ABUORABI, ST
中科院分区：
文献类型：
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作者：
ABUORABI, ST
“获得了与理论值一致的元素分析（C，N），并提交审查。6将CDCl 3-Me 2SO-d 6用作除用于化合物III的CDCl 3之外的所有化合物的NMR溶剂。4-羟基-1-苄基-4，5-二氢-5，7-庚基-6（2 H）-环庚三唑酮（IVa）。4-羟基-1-苄基-4，5-二氢-5，7-辛-6（2 β）-环庚三唑酮（IVb）。4-羟基-苄基-4，5-二氢-5，7-壬基-6（2 H）-环庚三唑酮（IVc）。环十五烷酮（IId）。但当I与IIa-c在相同条件下缩合时，得到相应的羟基环庚三唑酮（IVa-c）（方案I）。该1：1环加成与邻苯二甲醛和环酮之间的已知环加成非常类似（3，4）。
" Elemental analysis,(C,, N) in agreement with theoretical values were obtained and submitted for review. 6 CDCl3-Me2SO-d6 was used as the NMR solvent for all compounds except CDC13 used for compound III. 4-Hydroxy-l-benzyl-4, 5-dihydro-5, 7-heptano-6 (2H)-cycloheptatriazolone (IVa). 4-Hydroxy-l-benzyl-4, 5-dihydro-5, 7-octano-6 (2fl)-cycloheptatriazolone (IVb). 4-Hydroxyl-benzyl-4, 5-dihydro-5, 7-nonano-6 (2H)-cycloheptatriazolone (IVc). cyclopentadecanone (IId). But when I was condensed with I Ia-c under the same condition, the corresponding hydroxycycloheptatriazolones (IVa-c) were obtained (Scheme I). This 1: 1 cyclic addition is closely analogous to known cycloaddition between phthalaldehyde and cyclic ketones (3, 4).