Comparison of morbidity in children requiring abdominal radiation and chemotherapy, with and without total parenteral nutrition.
Comparison of morbidity in children requiring abdominal radiation and chemotherapy, with and without total parenteral nutrition.
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需要腹部放疗和化疗、有和没有全肠外营养的儿童的发病率比较。
DOI：
10.1016/s0022-3476(82)80695-1
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Tamaroff,M
中科院分区：
文献类型：
--
作者：
Ghavimi,F;Shils,ME;Scott,BF;Brown,M;Tamaroff,M
We evaluated the effectiveness of total parenteral nutrition and placing the “bowel at rest”, as compared to that of ad libitum food intake, on nutritional status and tolerance to combined chemotherapy and radiotherapy in a randomized, prospective trial in children with previously untreated malignancy requiring abdominal and pelvic irradiation and chemotherapy. Administration of TPN was found to be safe and efficacious in maintaining the children in good nutritional status during combined therapy; one-third of the control patients became malnourished and required TPN. There was no beneficial effect of “bowel at rest” and TPN on the ability of patients to tolerate combined therapies in terms of decreased toxicity; however, use of TPN was associated with improved adherence to chemotherapy schedules. Following termination of TPN or ad libitum food intake, and while receiving chemotherapy, the majority of the children who had previously received TPN lost significant weight. To date there has been no difference in mortality rate between the control and TPN groups. Although we conclude that TPN per se had little beneficial effect beyond that of maintaining good nutritional status, every child undergoing intensive combined therapy should have early and periodic assessments of nutritional status, so that the early signs of malnutrition can be detected, and the adverse effects of malnutrition can be prevented by nutritional replenishment, by TPN, or by other methods.
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儿童晚期胚胎横纹肌肉瘤的多学科治疗。
DOI：
--
发表时间：
1981
期刊：
National Cancer Institute monograph
影响因子：
--
作者：
Ghavimi,F;Exelby,PR;Jereb,B;Lieberman,PH;Scott,BF;Kosloff,C
通讯作者：
Kosloff,C
癌症引起的营养问题。
DOI：
10.1016/s0025-7125(16)31656-x
发表时间：
1979
期刊：
The Medical clinics of North America
影响因子：
--
作者：
M. E. Shils
通讯作者：
M. E. Shils
静脉营养过度作为癌症化疗的辅助手段。
影响因子：
3
作者：
E. Copeland;B. Macfadyen;V. Lanzotti;S. Dudrick
通讯作者：
S. Dudrick
影响因子：
10.5
作者：
S. Dudrick;J. M. Long
通讯作者：
J. M. Long
静脉营养过度作为 5-氟尿嘧啶癌症化疗的辅助手段。
DOI：
10.1016/0022-4804(75)90108-0
发表时间：
1975
期刊：
The Journal of surgical research
影响因子：
--
作者：
E. Souchon;E. Souchon;E. Copeland;E. Copeland;Patti Watson;Patti Watson;S. Dudrick;S. Dudrick
通讯作者：
S. Dudrick