Phylogenetic analysis of the hemagglutinin (H) gene of canine distemper viruses isolated from wild masked palm civets (Paguma larvata)
Phylogenetic analysis of the hemagglutinin (H) gene of canine distemper viruses isolated from wild masked palm civets (Paguma larvata)
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DOI：
10.1292/jvms.66.1575
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发表时间：
2004-12-01
影响因子：
1.2
通讯作者：
Kai, C
中科院分区：
文献类型：
--
作者：
Hirama, K;Goto, Y;Kai, C
对果子狸分离株Haku93和Haku00的血凝素(H)基因进行了分子分析。两株CDV的H基因均含有一个开放阅读框，编码607个氨基酸。CDV Haku93和Haku00株H基因的核苷酸和氨基酸序列与新野毒株如柳中和Tanu96有很高的相似性，但与旧疫苗株的同源性有限。Haku93和Haku00的潜在N-连接糖基化位点与其他新近分离的CDV株相同。系统进化分析表明，来源于果子狸的CDV毒株属于最近分离到的日本CDV毒株。
Hemagglutinin (H) gene of two CDV isolates, the Haku93 and Haku00 strains, from masked palm civets was molecularly analyzed. H genes of both two CDVs contained one open reading frame encoding 607 amino acids. Nucleotide and predicted amino acid sequences of H gene of the CDV Haku93 and Haku00 revealed high similarity to those of recent field isolates such as the Yanaka and Tanu96, while they showed limited identity to those of old vaccine strains. Potential N-linked glycosylation sites in both Haku93 and Haku00 were identical to other recent CDV isolates. Phylogenetic analysis revealed that the CDV strains derived from masked palm civets were classified into the group of recent Japanese CDV isolates.