Pregnant Women in Trials of Covid-19: A Critical Time to Consider Ethical Frameworks of Inclusion in Clinical Trials.
Pregnant Women in Trials of Covid-19: A Critical Time to Consider Ethical Frameworks of Inclusion in Clinical Trials.
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DOI：
10.1002/eahr.500060
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发表时间：
2020-07-01
影响因子：
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通讯作者：
Pope, Rachel
中科院分区：
文献类型：
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作者：
Farrell, Ruth;Michie, Marsha;Pope, Rachel
在这场前所未有的新型冠状病毒肺炎（COVID-19，即2019冠状病毒病）国际公共卫生危机中，伦理问题比比皆是。虽然在公共卫生伦理和临床伦理的交叉点上发生的社会和个人利益之间的权衡影响到所有人群，但这种权衡对孕妇以及她们何时能够获得新的Covid-19疗法和疫苗的问题特别重要。孕妇是一个“科学上复杂”的群体，其纳入临床研究必须考虑到怀孕的独特状态。然而，关于新型冠状病毒肺炎（COVID-19，即2019冠状病毒病）对孕妇影响的研究却滞后了。在匆忙预防和治疗SARS-CoV-2感染的过程中，至关重要的是优先考虑孕妇的利益，使她们能够自主地做出参与临床试验的知情决定。全球大流行要求重新审视将孕妇纳入研究的框架，因为这些妇女在新冠肺炎的预防和治疗中有着重要的利害关系。
Ethical issues abound during this unprecedented international public health crisis of Covid-19. While the trade-off between societal and individual interests that occurs at the intersection of public health ethics and clinical ethics affects all populations, this calculus has particular relevance for pregnant women and the question of when they will have access to new Covid-19 therapies and vaccines. Pregnant women are a "scientifically complex" population whose inclusion in clinical research must be done with consideration of the unique state of pregnancy. Yet research on the impact of Covid-19 on pregnant women is lagging. In a rush to prevent and treat SARS-CoV-2 infection, it is crucial that the interests of pregnant women be prioritized to enable them to make autonomous, informed decisions about participating in clinical trials. The global pandemic calls for a revisiting of frameworks for the inclusion of pregnant women in research, as these women have an important stake in the prevention and treatment of Covid-19.