Effect of ABO blood type on ovarian reserve in Chinese women
Effect of ABO blood type on ovarian reserve in Chinese women
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ABO血型对中国女性卵巢储备功能的影响
DOI：
10.1016/j.fertnstert.2014.09.008
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发表时间：
2014-12-01
影响因子：
6.7
通讯作者：
Qiao, Jie
中科院分区：
文献类型：
--
作者：
Lin, Shengli;Li, Rong;Qiao, Jie
目的：探讨ABO血型对中国女性卵巢储备的影响。设计：回顾性分析。设置：大学附属IVF中心。患者：回顾性分析涉及2006年至2012年期间接受体外受精和胚胎移植（IVF-ET）周期的35，479名女性。干预：无。主要结局指标：ABO血型与卵巢储备功能减退（DOR）之间的关系。在35，479名中国女性中，11，395人（32.12%）为B型，10，583人（29.83%）为O型，9，861人（27.79%）为A型，3，640人（10.26%）为AB型。在卵泡刺激素（FSH）水平10 IU/L的患者中，O型血的比例在统计学上显著较高。相反，在DOR女性中，B型和AB型血型的比例在统计学上显著较高。A型血与DOR的发生无关。多因素Logistic回归分析显示，O型血与DOR发生的相关性较低，而B抗原（B或AB型血）与DOR发生的相关性较高。O型血的女性患DOR的可能性在统计学上显著较低，而B抗原（B或AB型血）的女性患DOR的可能性在统计学上显著较高。A型血与卵巢储备无关。(C)2014年，美国生殖医学会（American Society for Reproductive Medicine）
Objective: To explore the effect of ABO blood type on ovarian reserve in Chinese women.Design: Retrospective analysis.Setting: University-affiliated IVF center.Patient( s): The retrospective analysis involved 35,479 women who underwent in vitro fertilization and embryo transfer (IVF-ET) cycles between 2006 and 2012.Intervention(s): None.Main Outcome Measure(s): The association between ABO blood types and diminished ovarian reserve (DOR).Result(s): Among 35,479 Chinese women, 11,395 (32.12%) had blood type B, 10,583 (29.83%) had blood type O, 9,861 (27.79%) had blood type A, and 3,640 (10.26%) had blood type AB. There was a statistically significantly higher percentage of blood type O among those with follicle-stimulating hormone (FSH) levels 10 IU/L. Conversely, among the women with DOR, there was statistically significantly higher percentage of those with blood types B and AB. Blood type A was not associated with DOR occurrence. Multivariate logistic regression analysis showed that blood type O was statistically significantly less often associated with DOR occurrence, whereas the B antigen (blood type B or AB) was statistically significantly associated with an increased risk of DOR.Conclusion(s): Our results have shown that there is an association between ABO blood type and DOR occurrence in Chinese women. Women with blood type O were statistically significantly less likely to have DOR, whereas those with B antigen (blood type B or AB) were statistically significantly more likely to have DOR. Blood type A was not associated with ovarian reserve. (C) 2014 by American Society for Reproductive Medicine.