General principles of migraine management: The changing role of prevention
General principles of migraine management: The changing role of prevention
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DOI：
10.1111/j.1526-4610.2005.4501002.x
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发表时间：
2005-04-01
期刊：
影响因子：
5
通讯作者：
Biondi, D
中科院分区：
文献类型：
--
作者：
Loder, E;Biondi, D
必须重新评估预防性治疗在偏头痛治疗中的作用。许多将从预防治疗中受益的患者没有接受预防治疗，许多患者可能会从更早和更积极地使用预防治疗中受益。治疗偏头痛的医生长期以来一直认识到，发作性偏头痛的一部分患者会演变为慢性形式的偏头痛，很难治疗，结果也很差。本文综述了目前和正在出现的预防性偏头痛治疗的证据，并提出了及时使用预防性治疗可能改变或防止向慢性偏头痛和极端残疾转化的可能性，而极端残疾是偏头痛人群中一小部分但意义重大的亚群的特征。随着对偏头痛的急性疼痛和其他症状的积极治疗，防止发展为这种疾病的严重形式将越来越成为治疗的重点和目标。
The role of preventive treatment in the management of migraine must be reassessed. Many patients who would benefit from preventive therapy do not receive it, and many might benefit from earlier and more aggressive use of preventive therapy. Physicians who treat migraine have long recognized that a subset of patients with episodic migraine evolve to chronic forms of the disorder that are difficult to treat and have a poor outcome. This article reviews the evidence for current and emerging prophylactic migraine treatment and raises the possibility that timely use of prophylactic treatment might modify or prevent the transformation to chronic migraine and the extreme disability that characterizes a small but significant subset of the migraine population. Along with aggressive treatment of the acute pain and other symptoms of migraine, prevention of progression to severe forms of this disorder will increasingly be a focus and goal of the treatment.