Retinal pigment epithelium decompensation. I. Clinical features and natural course.
Retinal pigment epithelium decompensation. I. Clinical features and natural course.
复制标题
视网膜色素上皮失代偿。
DOI：
10.1016/s0161-6420(84)34095-7
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发表时间：
1984
期刊：
影响因子：
13.7
通讯作者：
C. Schepens
中科院分区：
文献类型：
--
作者：
Jalkh Ae;N. Jabbour;Marcos Pereira de Ávila;Clement L. Trempe;C. Schepens
我们研究了97只眼(73例)，眼底镜下大体正常的后极外观与荧光血管造影所见的早期视网膜色素上皮(RPE)传递缺陷的多个斑块，以及晚期RPE染色的焦点区域之间的鲜明对比。染色主要位于RPE缺损区的上缘(63只眼)。确诊时患者的平均年龄为52.2岁，男女之比为3.5：1。除27眼确诊为中心性浆液性视网膜病变外，其余患者均无明显的眼部病史。32只连续观察的眼睛平均被跟踪了3.9年，其中30只眼睛出现了视力下降。
We studied 97 eyes (73 patients) that showed a sharp contrast between the grossly normal appearance of the posterior pole by funduscopy and the fluorescein angiography findings of multiple patches of retinal pigment epithelium (RPE) transmission defect in the early transit, associated with focal areas of RPE staining in the late transit. The staining was located primarily at the superior edge of the RPE defect (63 eyes). The average age of the patients was 52.2 years at the time of diagnosis, and the ratio of men to women was 3.5 to 1. Ocular histories were unremarkable, except for 27 eyes with documented central serous retinopathy. Thirty-two consecutive eyes have been followed for an average of 3.9 years, and 30 of those eyes have shown visual deterioration.