Effects of increased respiratory rate on cortical oxygenated hemoglobin during low-intensity exercise

Effects of increased respiratory rate on cortical oxygenated hemoglobin during low-intensity exercise
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DOI:
10.1016/j.resp.2021.103691
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发表时间:
2021-05-19
影响因子:
2.3
通讯作者:
Tsubaki, Atsuhiro
Tsubaki, Atsuhiro
中科院分区:
医学4区
文献类型:
--
作者:
Oyanagi, Keiichi;Tsubaki, Atsuhiro

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本研究旨在探讨呼气末CO2分压(PEtCO2)对近红外光谱(NIRS)测定的氧合血红蛋白(O(2)Hb)浓度的影响。参与者在正常和增加通气的条件下进行检查。我们测量了O(2)Hb、平均血压、皮肤血流量、PEtCO2、呼吸频率和运动期间最大摄氧量30%时的每分钟通气量。增加通气时运动时Δ O(2)、Hb和PEtCO2均低于正常通气时。Pearson积差相关分析显示,Δ O(2)Hb与Δ MAP、Δ SBF和PEtCO2之间存在显著正相关。Delta MAP、Delta SBF和PEtCO2的相关系数分别为0.249(p <0.001)、0.343(p < 0.001)和0.315(p < 0.001)。总之,我们确定自行车测力计运动期间通风增加是与PEtCO2和Delta O(2)Hb显着较低相关的重要因素。
This study aimed to examine whether the end-tidal partial pressure of CO2 (PEtCO2) affects the concentration of oxygenated hemoglobin (O(2)Hb) measured by near-infrared spectroscopy (NIRS). Participants were examined under the conditions of normal and increased ventilation. We measured O(2)Hb, mean blood pressure, skin blood flow, PEtCO2, respiratory rate, and minute volume at 30 % of the maximum oxygen uptake during exercise. Delta O(2)Hb and PEtCO2 during exercise were lower in the increased ventilation than in the normal ventilation condition. Pearson's product-moment correlation analysis showed a significant positive correlation between Delta O(2)Hb and Delta MAP, Delta SBF, and PEtCO2. Correlation coefficients were 0.249 (p < 0.001) for Delta MAP, 0.343 (p < 0.001) for Delta SBF, and 0.315 (p < 0.001) for PEtCO2. In conclusion, we identified increased ventilation during bicycle ergometer exercise as a significant factor associated with significantly low PEtCO2 and Delta O(2)Hb.