Weight Regain After Bariatric Surgery: Scope of the Problem, Causes, Prevention, and Treatment.
Weight Regain After Bariatric Surgery: Scope of the Problem, Causes, Prevention, and Treatment.
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DOI：
10.1007/s11892-023-01498-z
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发表时间：
2023-03
影响因子：
4.2
通讯作者：
Gadde, Kishore M.
中科院分区：
文献类型：
--
作者：
Noria, Sabrena F.;Shelby, Rita D.;Atkins, Katelyn D.;Nguyen, Ninh T.;Gadde, Kishore M.
虽然减肥手术是最有效的治疗严重肥胖，一部分患者经历临床显着的体重反弹（WR）与进一步从手术。这篇综述的目的是总结体重反弹的患病率、预测因素和原因。由于缺乏对其定义的共识，估计WR的患病率受到限制。虽然袖状胃切除术后胃底扩张和Roux-en-Y胃旁路术后胃-胃瘘等解剖失败可导致WR，但最常见的原因似乎是饮食行为失调/适应不良、生活方式因素和生理代偿机制。到目前为止，饮食，支持，行为和运动干预没有表现出临床上有意义的影响WR，药物治疗的证据有限。未来的研究应旨在更好地定义WR，以便开始了解病因。此外，需要在严格的随机对照试验中证明有效的非手术干预措施，用于预防和逆转减肥手术后的WR。
Although bariatric surgery is the most effective treatment of severe obesity, a proportion of patients experience clinically significant weight regain (WR) with further out from surgery. The purpose of this review is to summarize the prevalence, predictors, and causes of weight regain. Estimating the prevalence of WR is limited by a lack of consensus on its definition. While anatomic failures such as dilated gastric fundus after sleeve gastrectomy and gastro-gastric fistula after Roux-en-Y gastric bypass can lead to WR, the most common causes appear to be dysregulated/maladaptive eating behaviors, lifestyle factors, and physiological compensatory mechanisms. To date, dietary, supportive, behavioral, and exercise interventions have not demonstrated a clinically meaningful impact on WR, and there is limited evidence for pharmacotherapy. Future studies should be aimed at better defining WR to begin to understand the etiologies. Additionally, there is a need for non-surgical interventions with demonstrated efficacy in rigorous randomized controlled trials for the prevention and reversal of WR after bariatric surgery.
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DOI：
10.1136/bmj.g2646
发表时间：
2014-05-14
期刊：
BMJ (Clinical research ed.)
影响因子：
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作者：
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DOI：
10.1056/nejmoa2002449
发表时间：
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期刊：
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影响因子：
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作者：
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