Virulence of black-pigmented Bacteroides strains from periodontal pockets and other sites in experimentally induced skin lesions in mice.
Virulence of black-pigmented Bacteroides strains from periodontal pockets and other sites in experimentally induced skin lesions in mice.
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来自牙周袋和其他部位的黑色拟杆菌菌株在实验诱导的小鼠皮肤损伤中的毒力。
DOI：
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发表时间：
1982
影响因子：
3.5
通讯作者：
J. Graaff
中科院分区：
文献类型：
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作者：
T. V. Steenbergen;P. Kastelein;J. Touw;J. Graaff
采用单一感染的动物模型，研究了不同黑色素类杆菌菌株(BPB)的毒力。将细菌悬液注射到小鼠背部皮下。4天后处死小鼠，进行组织学检查。牙龈类杆菌，主要从与成人破坏性牙周炎有关的龈下菌斑中分离出来。以引起弥漫性炎症为特征，主要导致重力脓肿或粘液性脓肿。从牙周炎或牙周炎中分离到的中间类黑拟杆菌常在注射部位引起局限性脓肿。从非口腔部位分离的溶糖类杆菌大多引起局部炎症，产黑类杆菌亚种致炎作用较小。
The virulence of different black-pigmented Bacteroides strains (BPB) was studied using monoinfections in an experimental animal model. Bacterial suspensions were injected subcutaneously in the back of mice. After four days the mice were killed and the induced inflammations were examined histologically. Bacteroides gingivalis strains, which are mostly isolated from subgingival plaque associated with adult destructive periodontitis. were characterized by inducing a spreading type of inflammation, mostly resulting in a gravity abscess or a phlegmonous abscess. Strains of Bacteroides melaranogenicus subspecies intermedius, isolated from gingivitis or periodontitis, always induced a localized abscess at the site of injection. Most Bacteroides asaccharolyticus strains, which are isolated from nonoral sites, caused a localized inflammation, and Bacteroides melaninogenicus subspecies melaninogenicus strains caused only minimal inflammation.