Retroviral gene therapy and its application in oncohematology.
Retroviral gene therapy and its application in oncohematology.
复制标题
逆转录病毒基因治疗及其在肿瘤血液学中的应用。
DOI：
10.1089/hum.1992.3.3-285
复制
发表时间：
1992
影响因子：
4.2
通讯作者：
M. Favrot
中科院分区：
文献类型：
--
作者：
Y. Merrouche;M. Favrot
最近在法国阿纳西的massarieux基金会的支持下组织了一次题为“胎儿和新生儿细胞移植和逆转录病毒基因治疗”的讨论会，来自欧洲国家和美国的100名科学家和临床医生参加了这次讨论会。会议的最后一天重点讨论了肿瘤血液学中的逆转录病毒基因治疗。演讲者为基因转移的治疗应用提供了基础，并指出了在不久的将来需要遵循的实际方向。虽然一开始可能主要局限于对人类细胞的体外操作，但基因治疗已经适用于治疗遗传性疾病、癌症和病毒感染。临床医生和科学家在会议期间提出的问题的性质很好地说明了基因治疗的现实。
A symposium entitled "Foetal and Neonatal Cell Transplantation and Retroviral Gene Therapy" recently organized under the aegis of the Mérieux Foundation in Annecy, France, brought together 100 scientists and clinicians from European countries and the United States. The last day of the meeting focused on retroviral gene therapy in oncohematology. The speakers provided the basis for therapeutic applications of gene transfer and showed practical directions to be followed in the near future. Although it may be mainly restricted to in vitro manipulation of human cells at start, gene therapy is already applicable to the treatment of genetic disorders, cancer, and viral infections. The reality of gene therapy was well illustrated by the nature of the questions raised by clinicians and scientists during the meeting.