Living Donor Liver Transplantation with Left Liver Graft
Living Donor Liver Transplantation with Left Liver Graft
复制标题
活体肝移植（左肝移植）
DOI：
10.1111/j.1600-6143.2004.00548.x
复制
发表时间：
2004
影响因子：
8.8
通讯作者：
A. Pinna
中科院分区：
文献类型：
--
作者：
M. Masetti;A. Siniscalchi;L. D. Pietri;V. Braglia;F. Benedetto;N. Cautero;B. Begliomini;A. Romano;Charles M. Miller;G. Ramacciato;A. Pinna
LDLT的小尺寸综合征与移植物暴露于过度门静脉灌注有关。通过术中调节门静脉移植物流入，可以预防LDLT移植物过度灌注。我们报道了一个成功利用左叶的LDLT， GV/SLV仅为20%。一例43岁患者在我院接受了LDLT治疗。在无肝期，使用吻合于右门静脉分支和右肝静脉之间的间置静脉移植物进行门静脉-全身分流。移植物再灌注后行脾切除术。记录门静脉压力、门静脉流量和肝动脉流量。门静脉压力和流量下降，分流术得以保留。受者术后的特点是移植物功能良好。通过利用移植物的流入调节，可以成功地预防移植物过度灌注引起的小尺寸综合征。该策略允许在成人对成人活体供体肝移植中使用左肝。
Small‐for‐size syndrome in LDLT is associated with graft exposure to excessive portal perfusion. Prevention of graft overperfusion in LDLT can be achieved through intraoperative modulation of portal graft inflow. We report a successful LDLT utilising the left lobe with a GV/SLV of only 20%. A 43 year‐old patient underwent to LDLT at our institution. During the anhepatic phase a porto‐systemic shunt utilizing an interposition vein graft anastomosed between the right portal branch and the right hepatic vein was performed. After graft reperfusion splenectomy was also performed. Portal vein pressure, portal vein flow and hepatic artery flow were recorded. A decrease of portal vein pressure and flow was achieved, and the shunt was left in place. The recipient post‐operative course was characterized by good graft function. Small‐for‐size syndrome by graft overperfusion can be successfully prevented by utilizing inflow modulation of the transplanted graft. This strategy can permit the use of left lobe in adult‐to‐adult living donor liver transplantation.
H.Furukawa：“成人活体肝移植成功的移植物大小的限制是多少？”移植论文集。
DOI：
--
发表时间：
--
期刊：
影响因子：
--
作者：
通讯作者：
--