FACTORS CONCERNED IN THE POLYCYTHEMIA PRODUCED BY THE SUBCUTANEOUS INJECTION OF EPINEPHRINE
FACTORS CONCERNED IN THE POLYCYTHEMIA PRODUCED BY THE SUBCUTANEOUS INJECTION OF EPINEPHRINE
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肾上腺素皮下注射引起红细胞增多症的相关因素
DOI：
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发表时间：
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影响因子：
15.3
通讯作者：
E. E. Nelson
中科院分区：
文献类型：
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作者：
C. W. Edmunds;E. E. Nelson
皮下注射肾上腺素1毫克。每公斤的体重会导致红细胞增多症、网织红细胞增加和年轻形式的多形核白细胞增加。毫无疑问，红细胞增多症部分是一种浓缩现象，但这些年轻细胞数量的增加被认为是同时存在造血器官细胞排出的证据，这是由于药物对它们的影响。通过持续刺激被切断的坐骨神经的外周端，获得了类似的效果。
The subcutaneous injection of epinephrine in doses of 1 mg. per kilo brings about a polycythemia, an increase in reticulocytes, and an increase in young forms of polymorphonuclear leucocytes. The polycythemia is no doubt in part a concentration phenomenon, but the presence of these young cells in increasing numbers is believed to be evidence that there is at the same time a discharge of cells from the blood-forming organs, due to the effect of the drug upon them. A similar effect is obtained by continued stimulation of the peripheral ends of the cut sciatic nerves in the curarized animal.