Characterization of the phenolic composition and antimicrobial activities of Turkish medicinal plants
Characterization of the phenolic composition and antimicrobial activities of Turkish medicinal plants
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DOI：
10.1080/13880200902878069
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发表时间：
2009-07-01
影响因子：
3.8
通讯作者：
Ates, Mustafa
中科院分区：
文献类型：
--
作者：
Askun, Tulin;Tumen, Gulendam;Ates, Mustafa
本文研究了五种唇形科植物甲醇提取物的抑菌和抗分枝杆菌活性，这些植物通常用于治疗感冒、胃痛和咽喉痛，毛鼠尾草，白花铁蕨莫尔。（特有种）、细枝铁蕨（Sideritis leptoclada O.）施瓦茨和P. H. Davis，（特有）和Origanum onites L.，并采用高效液相色谱法测定了它们的酚类化合物。分析了对金黄色葡萄球菌、表皮葡萄球菌、粪肠球菌、蜡样芽孢杆菌、大肠杆菌、鼠伤寒沙门氏菌、产气肠杆菌和肺炎克雷伯氏菌的抗菌活性。测定抗结核分枝杆菌的抗分枝杆菌活性。对S.菌和大肠产气单胞菌S. fruticosa; E. coli和S.鼠伤寒沙门氏菌（E. typhimurium）;产气单胞菌S. tomentosa; S. typhimurium和E.产气单胞菌S. leptoclada和S.鼠伤寒沙门氏菌（E. typhimurium）; aerogenes和S. epidermidis由O.，分别。抗分枝杆菌活性以S.绒毛草S. fruticosa（MIC 392 μ g/mL）和O. Oonites（MIC 784 μ g/mL）对M.结核S. albiflora的迷迭香酸和香芹酚含量较低，对除K.肺炎克雷伯氏菌（B. pneumoniae）、B. cereus和M.结核体外活性和民族植物学使用之间的相关性进行了评估。
In this paper, antibacterial and antimycobacterial activity of five Labiatae plant methanol extracts, commonly used for treating cold, stomachache, and sore throat, Salvia fruticosa Mill., Salvia tomentosa Mill., Sideritis albiflora Hub.-Mor. (endemic), Sideritis leptoclada O. Schwarz & P. H. Davis, (endemic), and Origanum onites L., were investigated, and their phenolic compounds were determined by HPLC. Antibacterial activity was analyzed against Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Bacillus cereus, Escherichia coli, Salmonella typhimurium, Enterobacter aerogenes, and Klebsiella pneumoniae. Antimycobacterial activity was assayed against Mycobacterium tuberculosis. The best antibacterial activity (MIC 640 mu g/mL) was shown against S. typhimurium and E. aerogenes by S. fruticosa; E. coli, and S. typhimurium, E. aerogenes by S. tomentosa; S. typhimurium, and E. aerogenes by S. leptoclada and S. typhimurium, E. aerogenes and S. epidermidis by O. onites, respectively. The best antimycobacterial activity (MIC 196 mu g/mL) was shown by S. tomentosa. S. fruticosa (MIC 392 mu g/mL) and O. onites (MIC 784 mu g/mL) showed moderate activity against M. tuberculosis. S. albiflora, with low level rosmarinic acid and carvacrol content, showed inhibition against bacteria except K. pneumoniae, B. cereus and M. tuberculosis. The correlation between in vitro activity and ethnobotanical usage was evaluated.