Orthodontic Treatment for a Child with Melanotic Neuroectodermal Tumor during Infancy: A Case Report
Orthodontic Treatment for a Child with Melanotic Neuroectodermal Tumor during Infancy: A Case Report
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DOI：
10.3390/app112311541
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发表时间：
2021-12-01
影响因子：
2.7
通讯作者：
Mori, Yoshiyuki
中科院分区：
文献类型：
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作者：
Hichijo, Natsuko;Noguchi, Tadahide;Mori, Yoshiyuki
背景：婴儿期黑色素神经外胚层肿瘤（MNTI）是一种非常罕见的肿瘤，对MNTI患者进行正畸治疗的病例报道可能以前未见报道。本文描述了一名7岁女孩下颌骨MNTI的正畸治疗。病例：主诉为前牙合。虽然她在8个月大时被诊断为MNTI，但它仍然是亚临床的。因此，她一直定期随访计算机断层扫描（CT）和磁共振（MR）成像，没有积极的治疗。我们曾担心在正畸治疗中改变她的咬合位置对下颌骨的刺激。因此，我们向她和她的家人充分解释正畸治疗有加重MNTI的风险。然而，他们希望治疗包括上颌前伸和缓慢扩张，以纠正前交叉咬合和促进恒牙萌出。经过19个月的积极正畸治疗，前牙合得到改善，恒牙萌出进展良好。CT和MR成像均未发现MNTI进展和恶化的证据。由于观察期还很短，我们需要对她的咬合和MNTI进行仔细和长期的随访。此外，当我们遇到没有以往经验和报告的罕见病例时，知情同意尤为重要。
Background: Melanotic neuroectodermal tumor of infancy (MNTI) is a very rare tumor, and case reports of orthodontic treatment for patients with MNTI may be previously unreported. This article describes the orthodontic treatment for a 7-year-old girl with MNTI in the mandible. Case: Her chief complaint was anterior crossbite. Although she had an MNTI diagnosis at the age of 8 months, it remained subclinical. Therefore, she has been regularly followed-up by computed tomography (CT) and magnetic resonance (MR) imaging without aggressive treatment. We had worried about the stimulation of MNTI on the mandible by changing her occlusal position with orthodontic treatment. Therefore, we sufficiently explained to her and her family that orthodontic treatment was at risk for worsening MNTI. However, they desired treatment that consisted of maxillary protraction and slow expansion to correct anterior crossbite and encourage the permanent tooth eruption. After 19 months of active orthodontic treatment, the anterior crossbite was improved, and the eruption of permanent teeth made good progress. No evidence of progression and exacerbation of MNTI has been found by both CT and MR imaging. As the observation period is still short, we need a careful and long-term follow-up of her occlusion and MNTI. Furthermore, when we encounter rare cases without previous experience and reports, informed consent was of particular importance.