Metabolic changes in the blastocysts of mice and rats during delayed implantation.

Metabolic changes in the blastocysts of mice and rats during delayed implantation.
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小鼠和大鼠的囊胚在延迟着床期间的代谢变化。

DOI:
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发表时间:
1974
期刊:
Journal of Reproduction and Fertility
影响因子:
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通讯作者:
H. Weitlauf
H. Weitlauf
中科院分区:
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文献类型:
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作者:
H. Weitlauf

文献摘要

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The duration of the preimplantation period is not rigidly fixed in mice and rats. Although attachment of embryos to the uterine epithelium normally occurs late on the 5th day after fertilization, it may be delayed for days or weeks by concurrent lactation (naturally delayed implantation) or maternal ovariectomy (experimentally delayed implantation). It has long been known that the development of such 'delayed implanting' embryos is arrested at the blastocyst stage, and it has recently been shown that their overall embryonic metabolism is reduced. This depressed metabolic rate may be related to the ability of embryos to survive the prolonged free-living phase associated with delayed implantation. of in normal under for further