In vivo differentiation of astrocytic brain tumors and isolated demyelinating lesions of the type seen in multiple sclerosis using 1H magnetic resonance spectroscopic imaging
In vivo differentiation of astrocytic brain tumors and isolated demyelinating lesions of the type seen in multiple sclerosis using 1H magnetic resonance spectroscopic imaging
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DOI：
10.1002/ana.410440222
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发表时间：
1998-08-01
影响因子：
11.2
通讯作者：
Arnold, DL
中科院分区：
文献类型：
--
作者：
De Stefano, N;Caramanos, Z;Arnold, DL
我们使用计算机模式识别的质子磁共振波谱图像数据，以区分脑肿瘤和大型，孤立的，脱髓鞘病变的多发性硬化症的类型。留一线性判别分析正确分类共振配置文件从5个急性脱髓鞘病变，20低级别星形细胞瘤，22 anoplastic星形细胞瘤，和24胶质母细胞瘤。非急性病变的分类需要进一步的发展，因为脱髓鞘病变的代谢谱会随着时间的推移而演变。
We used computer pattern recognition of proton magnetic resonance spectroscopic image data to differentiate between brain tumors and large, isolated, demyelinating lesions of the type seen in multiple sclerosis. Leave-one-out linear discriminant analyses correctly classified resonance profiles from five acute demyelinating lesions, 20 low-grade astrocytomas, 22 anoplastic astrocytomas, and 24 glioblastomas. Classification of nonacute lesions will require further development, as the metabolic profiles of demyelinating lesions evolve over time.