Ensembl's 10th year.
Ensembl's 10th year.
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DOI：
10.1093/nar/gkp972
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发表时间：
2010-01
影响因子：
14.9
通讯作者：
Searle SM
中科院分区：
文献类型：
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作者：
Flicek P;Aken BL;Ballester B;Beal K;Bragin E;Brent S;Chen Y;Clapham P;Coates G;Fairley S;Fitzgerald S;Fernandez-Banet J;Gordon L;Gräf S;Haider S;Hammond M;Howe K;Jenkinson A;Johnson N;Kähäri A;Keefe D;Keenan S;Kinsella R;Kokocinski F;Koscielny G;Kulesha E;Lawson D;Longden I;Massingham T;McLaren W;Megy K;Overduin B;Pritchard B;Rios D;Ruffier M;Schuster M;Slater G;Smedley D;Spudich G;Tang YA;Trevanion S;Vilella A;Vogel J;White S;Wilder SP;Zadissa A;Birney E;Cunningham F;Dunham I;Durbin R;Fernández-Suarez XM;Herrero J;Hubbard TJ;Parker A;Proctor G;Smith J;Searle SM
Ensembl（http://www.ensembl.org）整合了一套全面的脊索动物基因组的基因组信息，特别侧重于人类、小鼠、大鼠、斑马鱼和其他高价值测序基因组的资源。除了针对基因组变异、功能和进化的特定资源外，我们还为所有支持的物种提供完整的基因注释。Ensembl数据可以通过多种格式获取，包括通过我们的基因组浏览器、应用程序编程接口（API）和BioMart。今年是Ensembl成立十周年，在此期间，随着基因组技术的进步，该项目不断发展。截至第56版（2009年9月），Ensembl支持51个物种，包括狨猴、猪、斑胸草雀、蜥蜴、大猩猩和沙袋鼠，这些都是在过去一年中新增的。自我们上次报告以来，Ensembl的主要新增内容和改进包括纳入人类GRCh37组装版本，增强了Ensembl调控特征的可视化和数据挖掘选项，以及我们软件基础设施的持续开发。
Ensembl (http://www.ensembl.org) integrates genomic information for a comprehensive set of chordate genomes with a particular focus on resources for human, mouse, rat, zebrafish and other high-value sequenced genomes. We provide complete gene annotations for all supported species in addition to specific resources that target genome variation, function and evolution. Ensembl data is accessible in a variety of formats including via our genome browser, API and BioMart. This year marks the tenth anniversary of Ensembl and in that time the project has grown with advances in genome technology. As of release 56 (September 2009), Ensembl supports 51 species including marmoset, pig, zebra finch, lizard, gorilla and wallaby, which were added in the past year. Major additions and improvements to Ensembl since our previous report include the incorporation of the human GRCh37 assembly, enhanced visualisation and data-mining options for the Ensembl regulatory features and continued development of our software infrastructure.