BIOMECHANICAL PROPERTIES OF DUODENAL WALL AND DUODENAL TONE DURING PHASE-I AND PHASE-II OF THE MMC
BIOMECHANICAL PROPERTIES OF DUODENAL WALL AND DUODENAL TONE DURING PHASE-I AND PHASE-II OF THE MMC
复制标题
DOI：
10.1152/ajpgi.1992.263.5.g795
复制
发表时间：
1992-11-01
影响因子：
--
通讯作者：
CHRISTENSEN, J
中科院分区：
文献类型：
--
作者：
GREGERSEN, H;ORVAR, K;CHRISTENSEN, J
我们使用了一种新的方法，阻抗测面积法，看看在顺应性，张力和扩张引起的蠕动活动的变化，在第一阶段和第二阶段的迁移性肌电复合体（MMC）在人类十二指肠。在十二指肠内逐步充盈球囊，压力高达30 cmH 2 O，同时测量压力和球囊横截面积（CSA）。根据这些测量值计算生物力学壁参数。在6例受试者中记录了9例十二指肠III期。球囊压力为20 cmH 2 O时，早期I相CSA为266（236-324）mm 2，晚期II相CSA为385（276-474）mm 2，两组比较差异有统计学意义（P < 0.05）。球囊扩张在I期不引起收缩，而在II期晚期，球囊扩张使球囊近端收缩活动增加60%（P < 0.05），球囊远端收缩活动增加4%。阶段I中球囊压力在10和30 cmH 2 O之间的阶梯扩张将CSA从40（30-81）增加到645（603-704）mm 2。它使周向壁张力从35（28-63）增加到429（402-466）mm × cm H2O，压力弹性模量从9.7（9.0-14.7）增加到33.8（27.6-33.8）cm H2O。因此，第一阶段和第二阶段的遵守情况各不相同。这很可能是由I期平滑肌张力增加引起的。十二指肠壁硬度随着球囊压力的增加而增加。
We used a new method, impedance planimetry, to look at variations in compliance, tone, and distension-induced peristaltic activity during phase I and phase II of the migrating myoelectric complex (MMC) in the human duodenum. A balloon was inflated stepwise with pressures up to 30 cmH2O in the duodenum, while the pressure and balloon cross-sectional area (CSA) were measured simultaneously. The biomechanical wall parameters were calculated from these measurements. Nine duodenal phase IIIs were recorded in six subjects. A balloon pressure of 20 cmH2O induced a smaller CSA in early phase I [266 (236-324) mm2] than in late phase II [385 (276-474) mm2] (P < 0.05). Balloon distensions elicited no contractions in phase I, whereas they increased contractile activity 60% (P < 0.05) proximal to the balloon and 4% distal to the balloon in late phase II. Step distensions in phase I with balloon pressures between 10 and 30 cmH2O increased the CSA from 40 (30-81) to 645 (603-704) mm2. It increased circumferential wall tension from 35 (28-63) to 429 (402-466) mm x cmH2O and the pressure elastic modulus from 9.7 (9.0-14.7) to 33.8 (27.6-33.8) cmH2O, respectively. Thus compliance differs from phase I to phase II. This is most likely caused by increased smooth muscle tone during phase I. Duodenal wall stiffness increases with the balloon pressure applied.