3-DIMENSIONAL MOTION AND DEFORMATION OF THE HEART WALL - ESTIMATION WITH SPATIAL MODULATION OF MAGNETIZATION - A MODEL-BASED APPROACH

3-DIMENSIONAL MOTION AND DEFORMATION OF THE HEART WALL - ESTIMATION WITH SPATIAL MODULATION OF MAGNETIZATION - A MODEL-BASED APPROACH
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DOI:
10.1148/radiology.185.1.1523316
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发表时间:
1992-10-01
期刊:
影响因子:
19.7
通讯作者:
AXEL, L
AXEL, L
中科院分区:
医学1区
文献类型:
--
作者:
YOUNG, AA;AXEL, L

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提出了一种用于从心肌的标记磁共振图像中对心脏的三维(3D)运动和变形进行体内估计的方法。该方法是基于一个3D可变形模型,适合在两个视图(短轴和长轴),这导致在一个全面的运动学模型的左心室的动态几何标记点的运动。将该方法应用于在四名健康志愿者中获得的数据,并根据模型内的位置合并数据。分析建模表明,所计算的应变场是相对不变的类型的平滑约束应用,最大的误差是在圆周径向剪切应变。从模型中提取的位移、扭转和应变与先前的二维MR成像分析和涉及在犬心肌中植入不透射线珠的3D研究结果一致。模型驱动的方法提供了一个准确和灵活的技术,在人体心脏的三维在体变形的非侵入性估计。
A method for in vivo estimation of the three-dimensional (3D) motion and deformation of the heart from tagged magnetic resonance images of the myocardium is presented. The method is based on a 3D deformable model fitted to the motion of tagged points in two views (short and long axes), which results in a comprehensive kinematic model of the dynamic geometry of the left ventricle. The method was applied to data obtained in four healthy volunteers, and data were pooled according to position within the model. Analytic modeling demonstrated that the calculated strain field was relatively invariant to the type of smoothing constraint applied; the greatest error was in the circumferential-radial shear strain. Displacement, torsion, and strain extracted from the model agreed with previous results of two-dimensional MR imaging analyses and 3D studies involving the implantation of radiopaque beads in canine myocardium. The model-driven approach provides an accurate and flexible technique for noninvasive estimation of 3D in vivo deformation of the human heart.