Staphylococcus aureus and Streptococcus pneumoniae interaction and response to pneumococcal vaccination: Myth or reality?
Staphylococcus aureus and Streptococcus pneumoniae interaction and response to pneumococcal vaccination: Myth or reality?
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DOI：
10.1080/21645515.2015.1081321
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发表时间：
2016-02-01
影响因子：
4.8
通讯作者：
Regev-Yochay, Gili
中科院分区：
文献类型：
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作者：
Reiss-Mandel, Aylana;Regev-Yochay, Gili
S.金黄色葡萄球菌和肺炎是两种常见的病原体，也由大部分健康个体在鼻和鼻咽空间中携带。携带S.金黄色葡萄球菌和在来自不同地理区域的各种流行病学研究中报告了肺炎在儿童中的发生。大多数研究发现，S。肺炎链球菌和S.金黄色葡萄球菌仅对疫苗型S. pneumoniae菌株在这篇综述中，我们总结了各种建议的机制，这建议细菌干扰，并报告PCV介绍到目前为止，在不同的地理区域的临床意义。
S. aureus and S. pneumoniae are both common pathogens that are also carried by a large proportion of healthy individuals in the nasal and nasopharyngeal spaces. A negative association between carriage of S. aureus and S. pneumoniae has been reported in children in various epidemiologic studies from different geographical regions. Most studies found that the negative association between S. pneumoniae and S. aureus was significant only for carriage of vaccine-type S. pneumoniae strains. In this review, we summarize the various suggested mechanisms of this suggested bacterial interference, and the clinical implications reported following PCV introduction to date in various geographical regions.