Low-frequency oscillations arising from competitive interactions between visual stimuli in macaque inferotemporal cortex.

Low-frequency oscillations arising from competitive interactions between visual stimuli in macaque inferotemporal cortex.
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猕猴颞下皮层视觉刺激之间的竞争性相互作用引起的低频振荡。

DOI:
10.1152/jn.00158.2005
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发表时间:
2005
期刊:
Journal of neurophysiology.
影响因子:
--
通讯作者:
Olson,CarlR
Olson,CarlR
中科院分区:
--
文献类型:
--
作者:
Rollenhagen,JulianneE;Olson,CarlR

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猕猴下颞叶皮层(IT)中的一些神经元通过以约5Hz的频率以一系列清晰定义的爆发的动作电位来响应视觉刺激。本研究的目的是测试的假设,这些神经元的振荡反应取决于竞争性的相互作用与其他神经元选择不同的刺激。为了验证这一假设,我们监测了在其他已经可见的背景图像存在的情况下显示的探针图像的反应。两个刺激用于测试每个神经元:中央凹图像,当单独显示时,引起兴奋性反应(“对象”)和外围图像,当单独显示时,引起很少或没有活动(“侧翼”)。我们评估了在训练维持中央固定的猴子中分别和一起呈现这些图像的结果。出现了两个新现象。首先,在侧翼存在的情况下展示物体增强了对物体的响应的振荡分量的强度。这种效应在不同的任务环境中强度不同,可能取决于猴子对侧翼的注意力分配。第二,在物体存在的情况下显示侧翼有时会引起强烈的振荡,其中初始相位是负的。这是所有更引人注目的,因为侧翼本身引起很少或根本没有反应。这种效果是强大的,在不同的任务背景下不变。这些结果可以解释为两个神经元群体之间的竞争,一个选择性的对象和其他的侧翼,如果它被假定为每个人口的视觉反应受到疲劳。
Some neurons in the inferotemporal cortex (IT) of the macaque monkey respond to visual stimuli by firing action potentials in a series of sharply defined bursts at a frequency of about 5 Hz. The aim of the present study was to test the hypothesis that the oscillatory responses of these neurons depend on competitive interactions with other neurons selective for different stimuli. To test this hypothesis, we monitored responses to probe images displayed in the presence of other already visible backdrop images. Two stimuli were used in testing each neuron: a foveal image that, when displayed alone, elicited an excitatory response (the “object”) and a peripheral image that, when displayed alone, elicited little or no activity (the “flanker”). We assessed the results of presenting these images separately and together in monkeys trained to maintain central fixation. Two novel phenomena emerged. First, displaying the object in the presence of the flanker enhanced the strength of the oscillatory component of the response to the object. This effect varied in strength across task contexts and may have depended on the monkey's allocating attention to the flanker. Second, displaying the flanker in the presence of the object gave rise to sometimes strong oscillations in which the initial phase was negative. This was all the more striking because the flanker by itself elicited little or no response. This effect was robust and invariant across task contexts. These results can be accounted for by competition between two neuronal populations, one selective for the object and the other for the flanker, if it is assumed that the visual responses of each population are subject to fatigue.
DOI: 10.1016/0165-0270(88)90160-4
发表时间: 1988-12-01
影响因子: 3
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期刊: Neurosciences research
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影响因子: 3.2
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