Autopsy in suspected COVID-19 cases
Autopsy in suspected COVID-19 cases
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DOI：
10.1136/jclinpath-2020-206522
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发表时间：
2020-05-01
影响因子：
3.4
通讯作者：
Osborn, Michael
中科院分区：
文献类型：
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作者：
Hanley, Brian;Lucas, Sebastian B.;Osborn, Michael
自从严重急性呼吸综合征-冠状病毒-2在武汉爆发以来，中国现在已经蔓延到包括英国在内的世界多个国家，死亡人数不断增加。这将不可避免地导致与2019年冠状病毒病(新冠肺炎)相关的疑似尸检死亡人数增加。英国皇家病理学家学会发布了一份关于新冠肺炎验尸实践的简报，以此回应了这一担忧。下面的文章是对这些指导方针的总结和解释。报告包括对第3类危害生物的描述、对SARS-CoV-2病毒被归类的描述、对新冠肺炎病理和尸检结果的现有已知情况的简要描述、对新冠肺炎疑似病例进行尸检的建议摘要以及在尸检中作出诊断的技术。结论是考虑了此类病例的临床病理相关性和通报情况。
The severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) outbreak in Wuhan, China has now spread to many countries across the world including the UK with an increasing death toll. This will inevitably lead to an increase in the number of suspected coronavirus disease 2019 (COVID-19)-related deaths at autopsy. The Royal College of Pathologists has responded to this concern with the release of a briefing on autopsy practice relating to COVID-19. The following article is a summary and interpretation of these guidelines. It includes a description of hazard group 3 organisms, the category to which SARS-CoV-2 has been assigned, a brief description of what is currently known about the pathological and autopsy findings in COVID-19, a summary of the recommendations for conducting autopsies in suspected COVID-19 cases and the techniques for making the diagnosis at autopsy. It concludes by considering the clinicopathological correlation and notification of such cases.