CHEMOTACTIC BEHAVIOR OF CAMPYLOBACTER-JEJUNI
CHEMOTACTIC BEHAVIOR OF CAMPYLOBACTER-JEJUNI
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DOI：
10.1128/iai.56.6.1560-1566.1988
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发表时间：
1988-06-01
影响因子：
3.1
通讯作者：
DOYLE, MP
中科院分区：
文献类型：
--
作者：
HUGDAHL, MB;BEERY, JT;DOYLE, MP
在不同氨基酸、碳水化合物、有机酸以及粘蛋白和胆汁的制剂和组分存在下，测定了空肠弯曲菌的趋化行为。L-岩藻糖是唯一的碳水化合物，L-天冬氨酸、L-半胱氨酸、L-谷氨酸和L-丝氨酸是唯一产生趋化（阳性）反应的氨基酸。有机酸的几种盐，包括丙酮酸盐、琥珀酸盐、富马酸盐、柠檬酸盐、苹果酸盐和α-酮戊二酸也是化学引诱物，胆汁（牛肉、鸡肉和牛胆）和粘蛋白（牛胆囊和猪胃）也是化学引诱物。胆汁中的大多数成分是化学排斥物，但粘蛋白成分是化学引诱物。C.空肠对L-岩藻糖（胆汁和粘蛋白的组分）的亲和力可能是生物体对胆囊和肠道的亲和力的重要因素。
The chemotactic behavior of Campylobacter jejuni was determined in the presence of different amino acids, carbohydrates, organic acids, and preparations and constituents of mucin and bile. L-Fucose was the only carbohydrate and L-aspartate, L-cysteine, L-glutamate, and L-serine were the only amino acids producing a chemotactic (positive) response. Several salts of organic acids, including pyruvate, succinate, fumarate, citrate, malate, and .alpha.-ketoglutarate, were also chemoattractants, as were bile (beef, chicken, and oxgall) and mucin (bovine gallbladder and hog gastric). Most constituents of bile tested individually were chemorepellents, but the mucin component was chemoattractant. The chemotactic behavior of C. jejuni toward L-fucose, a constituent of both bile and mucin, may be an important factor in the affinity of the organism for the gallbladder and intestinal tract.