Current pediatric and maternal lead levels in blood and breast milk in Andean inhabitants of a lead-glazing enclave
Current pediatric and maternal lead levels in blood and breast milk in Andean inhabitants of a lead-glazing enclave
复制标题
DOI：
10.1097/01.jom.0000137712.21963.76
复制
发表时间：
2004-09-01
影响因子：
3.2
通讯作者：
Ortega, F
中科院分区：
文献类型：
--
作者：
Counter, SA;Buchanan, LH;Ortega, F
出生前和出生后铅暴露可导致儿童神经发育障碍。作为一项正在进行的健康监测研究的一部分，比较了2003年在厄瓜多尔安第斯山区铅污染严重的村庄检测的90名儿童（当前组）和1996年至2000年期间检测的166名儿童（参照组）的血铅水平。参考组儿童的平均PbB水平为40 mug/dL（范围，6.2-119.1），显著高于当前组的平均PbB水平25.5 mug/dL（范围，2.1-94.3）（t检验，P = 0.0001）。方差分析显示，年龄和性别没有显著的主效应，当前组的年龄和性别之间没有显著的相互作用，但参考组的年龄与性别之间存在显著的相互作用（F = 5.96，P = 0.01）。回归分析显示，参考组中男性的PbB水平与年龄呈显著相关（r = 0.258，P = 0.01），而女性的相关性不显著。母乳中的铅水平从哺乳母亲的范围从0.4-20.5微克/升（平均值，4.6），和PbB水平在母乳喂养的母亲范围从4.5-35.2微克/分升（平均值，17.1）。母亲和婴儿的铅水平分别为4.6-27.4 mug/dL和3.9-33.5 mug/dL。结果表明，研究地区儿童的铅水平显着降低，并建议铅教育和预防计划有助于目前的减少。铅中毒。
Prenatal and postnatal lead (Pb) exposure may induce neurodevelopmental disabilities in children. As part of an ongoing health-monitoring stud),, blood lead (PbB) levels were compared in 90 children tested In 2003 (current group) and 166 children tested between 1996 and 2000 (reference group) in Ecuadorian Andean villages with high Pb contamination. The mean PbB level for children in the reference group was 40 mug/dL (range, 6.2-119.1), and significantly higher than the mean PbB level of 25.5 mug/dL (range, 2.1-94.3) for the current group) (t test, P = 0.0001). An analysis of variance revealed no significant main effects for age and gender and no significant interaction, between age and gender for the current group but a significant age by gender interaction for the reference group (F = 5.96, P = 0.01). Regression analysis revealed a significant correlation (r = 0.258, P = 0.01) between PbB level and age for males but not for females in the reference group. The Pb levels in breast milk from nursing mothers ranged from 0.4-20.5 mug/L (mean, 4.6), and the PbB levels in the breastfeeding mothers ranged from 4.5-35.2 mug/dL (mean, 17.1). The PbB levels of mother-infant pairs ranged from 4.6-27.4 mug/dL for mothers and 3.9-33.5 mug/dL for infants. The results showed significantly)) reduced PbB levels in children in the study area and suggest that a Pb education and prevention program contributed to the current reduction in. Pb intoxication.