Economic analysis in admitted patients with acute exacerbation of chronic obstructive pulmonary disease
Economic analysis in admitted patients with acute exacerbation of chronic obstructive pulmonary disease
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DOI：
10.1097/00029330-200804010-00003
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发表时间：
2008-04-05
影响因子：
6.1
通讯作者：
Wang Xin-Mao
中科院分区：
文献类型：
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作者：
Chen Ya-Hong;Yao Wan-Zhen;Wang Xin-Mao
北京慢性阻塞性肺疾病急性加重（AECOPD）的社会经济负担尚不完全清楚。研究AECOPD患者住院费用及相关因素。方法采用多中心、回顾性研究方法，对北京市4家医院（2家三级医院和2家11级医院）进行调查。纳入了2006年1月至12月住院的AECOPD患者。分析住院费用及其与疾病严重程度和治疗的关系。结果共纳入439例患者，其中男性294例（67.0%），平均年龄73.4岁。平均住院时间为20.7天。呼吸衰竭204例（46.5%），肺心病153例（34.9%），冠状动脉疾病123例（28.0%），高血压231例（52.6%），脑血管疾病70例（15.9%），肾功能衰竭32例（7.3%）。药品费用占总费用的比例最高（71.2%），其次是检验费（16.7%）、治疗费（9.7%）、氧气费（7.3%）、放射学费（4.5%）、检查费（4.5%）、床位费（4.1%）。相关分析显示，住院费用与年龄、住院天数、呼吸衰竭、肺心病、高血压等合并症呈正相关。对321例患者进行进一步分析。无创通气患者住院费用增加(P
Background The socio-economic burden of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in Beijing is not fully understood. The study investigated the hospitalization cost in patients with AECOPD and the associated factors.Methods A multi-center, retrospective study was conducted in the four hospitals in Beijing including two level III hospitals and two level 11 hospitals. Patients with AECOPD admitted to the hospitals between January and December in 2006 were enrolled. The hospitalization cost and its relationship with disease severity and treatment were analyzed.Results Totally 439 patients were enrolled with 294 men (67.0%) and a mean age 73.4 years. The mean hospital stay was 20.7 days. A total of 204 patients (46.5%) had respiratory failure, 153 (34.9%) with cor pulmonale, 123 (28.0%) with coronary artery disease, 231 (52.6%) with hypertension, 70 (15.9%) with cerebrovascular disease and 32 (7.3%) with renal failure. The percentage of drug cost to total cost was the highest (71.2%), followed by laboratory cost (16.7%), therapy cost (9.7%), oxygen cost (7.3%), radiology cost (4.5%), examination cost (4.5%), bed cost (4.1%). Correlation analysis showed that cost was positively correlated with age, hospitalization days, co-morbidities such as respiratory failure and cor pulmonale, hypertension. Three hundred and twenty-one patients were further analyzed. The hospitalization cost increased in patients with non-invasive ventilation (P