Effects of a short-term circuit weight training program on glycaemic control in NIDDM

Effects of a short-term circuit weight training program on glycaemic control in NIDDM
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DOI:
10.1016/s0168-8227(98)00027-8
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发表时间:
1998-04-01
影响因子:
5.1
通讯作者:
Stanton, KG
Stanton, KG
中科院分区:
医学3区
文献类型:
--
作者:
Dunstan, DW;Puddey, IB;Stanton, KG

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本研究评估短期循环负重训练(CWT)对NIDDM患者血糖控制的影响。27名未经训练、久坐不动的NIDDM受试者(平均年龄51岁)参加了一项为期8周的随机对照研究,包括每周3天CWT(n = 15)或无正式运动(对照)(n = 12)。所有受试者在整个过程中定期进行自我血糖监测。空腹血清葡萄糖和胰岛素测定后12小时的快速和口服葡萄糖耐量试验(75克)之前和之后8周。21例受试者完成了研究(CWT,n = 11)(对照,n = 10)。所有运动的力量在CWT后显著改善。使用随机效应模型进行的汇总时间序列分析显示,与对照组相比,CWT组自我监测的血糖水平总体下降。与对照组相比,CWT后葡萄糖(-213 mmol l(-1)/120 min,P < 0.05)和胰岛素(-6130 pmol l(-1)/120 min,P < 0.05)的曲线下面积均较基线值显著降低。在调整体重变化后,自我监测的葡萄糖水平和胰岛素曲线下面积的变化,但不是葡萄糖曲线下面积,仍然显着。因此,短期CWT可以提供一个实际的运动替代这种情况下的生活方式管理。(C)1998爱思唯尔科学爱尔兰有限公司保留所有权利。
This study assessed the effects of short-term circuit weight training (CWT) on glycaemic control in NIDDM. Twenty-seven untrained, sedentary subjects (mean age, 51) with NIDDM participated in an 8-week randomised, controlled study, involving either CWT 3 days/week (n = 15) or no formal exercise (control) (n = 12). All subjects performed regular self-blood glucose monitoring throughout. Fasting serum glucose and insulin were measured following a 12-h fast and during an oral glucose tolerance test (75 g) before and after 8 weeks. Twenty-one subjects completed the study (CWT, n = 11) (Control, n = 10). Strength for all exercises improved significantly after CWT. Pooled time-series analysis, using a random effects model, revealed an overall decrease in self-monitored glucose levels with CWT compared to controls. Significant reductions from baseline values were observed in both the glucose (- 213 mmol l(-1) per 120 min, P < 0.05) and insulin (- 6130 pmol l(-1) per 120 min, P < 0.05) area under the curve following CWT relative to controls. After adjustment for body mass changes, the change in self-monitored glucose levels and insulin area under the curve, but not glucose area under the curve, remained significant. Short-term CWT therefore may provide a practical exercise alternative in the lifestyle management of this condition. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.