Emerging trends in solution self-assembly of block copolymers
Emerging trends in solution self-assembly of block copolymers
复制标题
嵌段共聚物溶液自组装的新趋势
DOI：
10.1016/j.polymer.2020.122914
复制
发表时间：
2020-10-20
期刊：
影响因子：
4.6
通讯作者：
Liu, Shiyong
中科院分区：
文献类型：
--
作者：
Deng, Zhengyu;Liu, Shiyong
自从施陶丁格创立大分子科学以来，高分子化学的进步已经揭示了在分子尺度上控制化学结构的巨大途径。两亲性嵌段共聚物（BCP）作为一种典型的自组装聚合物，由不同的聚合物嵌段共价连接而成，可自发形成各种纳米结构，具有多种功能，尤其在纳米医学和生物材料领域有着广泛的应用。自组装过程可以发生在单链水平（即，链内折叠）或涉及具有相似和不同化学结构的多个链（即，链间关联）。这篇综述文章讨论了最近的趋势，有关解决方案自组装的BCP，包括形成倒置的中间相，自折叠成单链纳米粒子（SCNPs），区室化的纳米粒子与复杂的功能，和纳米结构的两亲性共聚物与精确的链长和预定的序列，突出选择的例子。
Since the foundation of macromolecular science by Staudinger, advances in polymer chemistry have unveiled enormous avenues for controlling chemical structures at the molecular scale. As a typical self-assembling polymer covalently linked by chemically distinct polymer blocks, amphiphilic block copolymers (BCPs) spontaneously form a variety of nanostructures with diverse functional applications, especially in the fields of nanomedicine and biomaterials. Self-assembling processes could occur at single chain level (i.e., intrachain folding) or involve multiple chains with similar and dissimilar chemical structures (i.e., interchain association). This review article discusses recent trends concerning solution self-assembly of BCPs, including the formation of inverted mesophases, self-folding into single-chain nanoparticles (SCNPs), compartmentalized nanoparticles with sophisticated functions, and nanostructures of amphiphilic copolymers with precise chain lengths and predetermined sequences, by highlighting selected examples.