Shear strain estimation and lesion mobility assessment in elastography
Shear strain estimation and lesion mobility assessment in elastography
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DOI：
10.1016/s0041-624x(99)00125-0
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发表时间：
2000-03-01
期刊：
影响因子：
4.2
通讯作者：
Ophir, J
中科院分区：
文献类型：
--
作者：
Konofagou, EE;Harrigan, T;Ophir, J
弹性成像通常沿声化/压缩轴测量正常应力分量并对其成像，即在轴向。我们最近已经证明，通过使用横向位移的RF回波段的内插和互相关法，可以以良好的精度测量和成像梁的横向位移和应变。这使得对所有三个主法向应变分量的估计和成像成为可能。一般来说，在应变估计方向以外的方向上的运动可能会导致去相关噪声，从而严重破坏估计。因此，采用一种校正方法来校正去相关运动的位移和应变估计。在这篇文章中，我们展示了如何使用修正的位移估计也可以估计和成像剪切应变分量。这可能使我们能够识别由于剪切应变引起的正常应变测量中的去相关噪声区域。透明应变估计提供了补充信息，可以根据不同组织元素的流动性来表征不同的组织元素。在乳房病变中，低活动度与恶性肿瘤有关。在活体病例之后，我们用2D模拟展示了如何通过剪切应变估计来实现对肿瘤移动性的评估。(C)2000由爱思唯尔科学公司出版。保留所有权利。
Elastography typically measures and images the normal sti ain component along the insonification/compression axis, i.e., in the axial direction. We have recently shown that, by using interpolation and cross-correlation methods of transversely displaced RF echo segments, it is possible to measure and image displacement and strain transversely to the beam with good precision. This enables the estimation and imaging of all three principal normal strain components. Generally, motion in a direction other than that in which strain is estimated may result in decorrelation noise, severely corrupting the estimates. Therefore, a correction method is applied to correct the displacement and strain estimates for decorrelating motion. In this paper, we show how corrected displacement estimates can also be used to estimate and image the shear strain components. This may allow us to identify regions of decorrelation noise in the normal strain measurement that are due to shear strain. Sheer strain estimates provide supplementary information, which can characterize different tissue elements based on their mobility. In the case of breast lesions, low mobility is related to malignancy. Following an in vivo case, we show with 2D simulations how assessment of tumor mobility can be achieved with shear strain estimation. (C) 2000 Published by Elsevier Science B.V. All rights reserved.