Labdane Diterpenoids and Shikimic Acid Derivatives from Araucaria cunninghamii
Labdane Diterpenoids and Shikimic Acid Derivatives from Araucaria cunninghamii
复制标题
南洋杉中的劳丹烷二萜和莽草酸衍生物
DOI：
10.1055/s-0030-1250570
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发表时间：
2011-03-01
期刊：
影响因子：
2.7
通讯作者：
Gao, Kun
中科院分区：
文献类型：
--
作者：
Chen, Jia;Chen, Jian-Jun;Gao, Kun
Four new (1-4) and two known compounds (5, 6) were isolated from the aerial parts of Araucaria cunninghamii. By analysis of UV, IR, MS, and NMR, the new compounds were identified as ent-19-(Z)-coumaroyloxylabda-8(17), 13(16), 14-triene (1), ent-19-(E)-coumaroyloxylabda-8(17), 13(16), 14-triene (2), shikimic acid n-butyl ester (3), and 5-(Z)-coumaroyloxyquinic acid n-butyl ester (4). Compounds 1 and 6 exhibited inhibitory activity against Escherichia coli, and compound 1 also exhibited moderate activity against human leukemia cells (HL-60) and human hepatoma cells (SMMC-7721) with IC50 values of 8.90 and 11.53 mu M, respectively.
