Short-Term Changes in Cardiovascular Hemodynamics in Response to Bariatric Surgery and Weight Loss Using the NexfinA® Non-invasive Continuous Monitoring Device: a Pilot Study
Short-Term Changes in Cardiovascular Hemodynamics in Response to Bariatric Surgery and Weight Loss Using the NexfinA® Non-invasive Continuous Monitoring Device: a Pilot Study
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DOI：
10.1007/s11695-017-2564-2
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发表时间：
2017-07-01
期刊：
影响因子：
2.9
通讯作者：
Buise, Marc P.
中科院分区：
文献类型：
--
作者：
Pouwels, Sjaak;Lascaris, Bianca;Buise, Marc P.
与健康个体相比，肥胖者的收缩压和舒张压、平均动脉压、心率和心输出量显著升高。本研究的目的是评估减肥手术前和手术后3个月的心血管血流动力学变化，纳入了2016年9月29日至2016年3月24日期间计划进行减肥手术的患者，并与24名健康人进行了比较。使用NexfinA（R）非侵入性连续血液动力学监测装置（Edwards Lifesciences/BMEYE B. V.，80名受试者分别包括在该研究中，56名肥胖患者计划进行减肥手术，24名健康个体。基线血流动力学测量显示心输出量存在显着差异（6.5 +/- 1.6 vs 5.7 +/- 1.6 l/min，p = 0.046），平均动脉压（107 +/- 19 vs 89 +/- 11 mmHg，p = 0.001），收缩压（134 +/- 24 vs 116 +/- 18 mmHg，p = 0.001）和舒张压（89 +/- 17 vs 74 +/- 10 mmHg，p = 0.001）和心率（87 +/- 12 vs 76 +/- 14 bpm，p = 0.02）。术后3个月，平均动脉压发生显著变化（89 ± 17 mmHg，p = 0.001），收缩压（117 +/- 24 mmHg，p = 0.001）和舒张压（71 ± 15 mmHg，p = 0.001），每搏输出量（82.2 +/- 22.4 ml，p = 0.03）和心率（79 +/- 17 bpm，p = 0.02）减肥手术后3个月，除心输出量和心脏指数外，血流动力学变量均出现显著改善，在患者组中。
Compared to healthy individuals, obese have significantly higher systolic and diastolic blood pressure, mean arterial pressure, heart rate, and cardiac output. The aim of this study was to evaluate cardiovascular hemodynamic changes before and 3 months after bariatric surgery.Patients scheduled for bariatric surgery between the 29th of September 2016 and 24th of March 2016 were included and compared with 24 healthy individuals. Hemodynamic measurements were performed preoperatively and 3 months after surgery, using the NexfinA (R) non-invasive continuous hemodynamic monitoring device (Edwards Lifesciences/BMEYE B.V., Amsterdam, the Netherlands).Eighty subjects were included in this study, respectively, 56 obese patients scheduled for bariatric surgery and 24 healthy individuals. Baseline hemodynamic measurements showed significant differences in cardiac output (6.5 +/- 1.6 versus 5.7 +/- 1.6 l/min, p = 0.046), mean arterial pressure (107 +/- 19 versus 89 +/- 11 mmHg, p = 0.001), systolic (134 +/- 24 versus 116 +/- 18 mmHg, p = 0.001) and diastolic blood pressure (89 +/- 17 versus 74 +/- 10 mmHg, p = 0.001), and heart rate (87 +/- 12 versus 76 +/- 14 bpm, p = 0.02) between obese and healthy subjects. Three months after surgery, significant changes occurred in mean arterial pressure (89 +/- 17 mmHg, p = 0.001), systolic (117 +/- 24 mmHg, p = 0.001) and diastolic blood pressure (71 +/- 15 mmHg, p = 0.001), stroke volume (82.2 +/- 22.4 ml, p = 0.03), and heart rate (79 +/- 17 bpm, p = 0.02)Three months after bariatric surgery, significant improvements occur in hemodynamic variables except cardiac output and cardiac index, in the patient group.