Sendai virus based direct cardiac reprogramming: what lies ahead?
Sendai virus based direct cardiac reprogramming: what lies ahead?
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DOI：
10.21037/sci.2018.10.02
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发表时间：
2018-10
影响因子：
--
通讯作者：
J. Engel;R. Ardehali
中科院分区：
文献类型：
--
作者：
J. Engel;R. Ardehali
影响全球3800万人的心力衰竭仍然是卫生保健领域的一个巨大挑战(1)。心力衰竭的病理涉及心肌细胞的死亡或功能障碍以及用非收缩瘢痕组织替代，因为成人心脏缺乏内源性修复机制来完全恢复损伤后的心功能，如心肌梗死(MI)。
Affecting over 38 million people worldwide, heart failure remains an immense challenge in health care (1). The pathology of heart failure involves death or dysfunction of cardiomyocytes and replacement with non-contractile scar tissue since the adult human heart lacks endogenous repair mechanisms to fully restore cardiac function after injury such as a myocardial infarction (MI).