Health-Related Qualities of Life in School-Aged Children with Bronchopulmonary Dysplasia.
Health-Related Qualities of Life in School-Aged Children with Bronchopulmonary Dysplasia.
复制标题
患有支气管肺发育不良的学龄儿童的健康相关生活质量。
DOI：
10.1016/j.jpeds.2023.113548
复制
发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Gaffin,JonathanM
中科院分区：
文献类型：
--
作者：
Sierra,Gabriella;Liu,JessicaP;Ith,Izabelle;Gudur,Divya;Cunningham,Deja;Dahlberg,SuzanneE;Beam,Kristyn;Gaffin,JonathanM
目的确定健康相关的生活质量（HRQOL）的学龄儿童支气管肺发育不良（BPD）使用标准化的患者报告的结果测量信息系统（PROMIS）assessmenttools.Study designThe室内空气质量和呼吸道疾病的儿童BPD研究是一个正在进行的观察性研究学龄儿童BPD。HRQOL在入组时通过3份PROMIS问卷、父母代理量表-全球健康7、父母代理心理压力经历-简表和父母代理概况-概况-25进行评估。PROMIS数据进行了测试显着偏离标准化的T-评分参考儿童的正常人群。ResultsEight-nine例受试者参加了AERO-BPD研究HRQOL的完整结果数据。平均年龄为9（±2）岁，43%为女性。平均呼吸支持天数总计96（±40）天。在所有领域，学龄儿童BPD报告类似或略好于参考样本的结果。低抑郁症的统计学显著性发现（P< .0001），疲劳（P<0.0001），疼痛（P< .0001）得分被发现;心理压力体验没有差异，（P= .87），全球健康（P= 0.06），焦虑（P= 0.08），关系（P= .80），和流动性（P= .59）domains.ConclusionsThis研究表明，儿童BPD可能有较少的抑郁，疲劳和疼痛HRQL比一般人群。一旦得到验证，这些发现可能会为照顾BPD儿童的父母和提供者提供保证。
ObjectiveTo determine health-related quality of life (HRQOL) of school-aged children with bronchopulmonary dysplasia (BPD) using the standardized Patient-Reported Outcomes Measurement Information System (PROMIS) assessment tools.Study designThe Indoor Air Quality and Respiratory Morbidity in Children with BPD Study is an ongoing observational study of school-aged children with BPD. HRQOL is assessed at enrollment by 3 PROMIS questionnaires, Parent Proxy Scale–Global Health 7, Parent Proxy Psychological Stress Experiences–Short Form, and the Parent Proxy Profile–Profile-25. PROMIS data were tested for significant deviation from the standardized T-Score references for normative populations of children.ResultsEighty-nine subjects enrolled in the AERO-BPD study had complete outcome data for HRQOL. The mean age was 9 (±2) years and 43% were female. Mean days on respiratory support totaled 96 (±40). Across all domains, school-aged children with BPD reported similar or slightly better outcomes than the reference sample. Statistically significant findings of lower depression (P< .0001), fatigue (P< .0001), and pain (P< .0001) scores were found; there was no difference in psychological stress experiences (P= .87), global health (P= .06), anxiety (P= .08), relationships (P= .80), and mobility (P= .59) domains.ConclusionsThis study demonstrated that children with BPD may have less depression, fatigue, and pain HRQL than the general population. Once validated, these findings may offer reassurance to parents and providers caring for children with BPD.