A recruitment model of quasi-linear power-law stress adaptation in lung tissue
A recruitment model of quasi-linear power-law stress adaptation in lung tissue
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DOI：
10.1007/s10439-007-9291-0
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发表时间：
2007-07-01
影响因子：
3.8
通讯作者：
Bates, Jason H. T.
中科院分区：
文献类型：
--
作者：
Bates, Jason H. T.
当肺组织经受应变阶跃时，它表现出作为时间的幂函数的应力适应曲线。此外，该幂函数与应变无关，即使组织的准静态应力-应变关系是高度非线性的。这种行为被称为准线性粘弹性，但其机械基础是未知的。我们描述了一个软组织流变学模型的基础上，连续招聘的麦克斯韦机构。该模型是均匀的元素的本构特性，但预测幂律应力松弛和准线性粘弹性，即使当模型的应力-应变行为是非线性的。该模型表明，肺组织中的应力松弛可以通过一系列微裂缝发生，这些微裂缝导致应力从一个局部应力承受区域传递到另一个局部应力承受区域。
When lung tissue is subjected to a step in strain, it exhibits a stress adaptation profile that is a power function of time. Furthermore, this power function is independent of the strain, even though the quasi-static stress-strain relationship of the tissue is highly nonlinear. Such behavior is known as quasi-linear viscoelasticity, but its mechanistic basis is unknown. We describe a model of soft tissue rheology based on the sequential recruitment of Maxwell bodies. The model is homogeneous in its elemental constitutive properties, yet predicts both power-law stress relaxation and quasi-linear viscoelasticity even when the stress-strain behavior of the model is nonlinear. The model suggests that stress relaxation in lung tissue could occur via a sequence of micro-rips that cause stresses to be passed from one local stress bearing region to another.