Domain definition and target classification for CASP6.
Domain definition and target classification for CASP6.
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CASP6 的域定义和目标分类。
DOI：
10.1002/prot.20717
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发表时间：
2005
期刊：
影响因子：
2.9
通讯作者：
DunbrackJr,RolandL
中科院分区：
文献类型：
--
作者：
Tress,Michael;Tai,Chin-Hsien;Wang,Guoli;Ezkurdia,Iakes;López,Gonzalo;Valencia,Alfonso;Lee,Byungkook;DunbrackJr,RolandL
CASP6的结构预测评估基于从实验确定的结构中分离出的单个结构域，这些结构域分为比较建模、褶皱识别和新的褶皱目标。领域定义是在自动领域解析程序的帮助下对结构进行视觉检查后定义的。结构域分类是通过将每个靶点过期时的目标结构与蛋白质数据库中的结构进行比较，以及各种基于序列和结构的方法来确定潜在的同源关系来确定的。蛋白质2005;增刊7:8-18。©2005 Wiley‐Liss, Inc。
Assessment of structure predictions in CASP6 was based on single domains isolated from experimentally determined structures, which were categorized into comparative modeling, fold recognition, and new fold targets. Domain definitions were defined upon visual examination of the structures with the aid of automated domain‐parsing programs. Domain categorization was determined by comparison of the target structures with those in the Protein Data Bank at the time each target expired and a variety of sequence and structure‐based methods to determine potential homologous relationships. Proteins 2005;Suppl 7:8–18. © 2005 Wiley‐Liss, Inc.