Extensive dental caries in a HIV positive adult patient on ART; case report and literature review
Extensive dental caries in a HIV positive adult patient on ART; case report and literature review
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DOI：
10.1186/s12903-018-0675-3
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发表时间：
2018-12-07
期刊：
影响因子：
2.9
通讯作者：
Sewankambo, Nelson K.
中科院分区：
文献类型：
--
作者：
Kalanzi, Dunstan;Mayanja-Kizza, Harriet;Sewankambo, Nelson K.
背景乌干达艾滋病病毒感染者（PLHIV）的估计人数为150万（7.3%）。截至2016年6月，60%（898，197）的艾滋病毒感染者已登记并接受抗逆转录病毒治疗（ART）。在科学文献中，艾滋病毒和ART对龋齿的影响仍然不明确。在Makerere大学健康科学学院牙科系的修复诊所，我们看到一些艾滋病毒感染者由于广泛的龋齿而需要用部分或全部假牙替换缺失的牙齿。在这里，我们报告的情况下，艾滋病毒阳性的女性患者广泛的龋齿，导致完全无牙颌，与心理压力和stigmatization.Case presentationA 52岁的病人，艾滋病毒阳性十四（14）年，并接受抗逆转录病毒治疗（ART）在过去的四年里，想更换她的牙齿有效的喂养和美容的原因。诊断为上颌和下颌牙弓部分无牙，牙12、15、25、34的颈部龋和牙11、13、22、35的残留根。口腔健康教育和口腔准备后，这名患者收到了一套可移动的丙烯酸全上下denture.ConclusionThis情况下，可能代表艾滋病毒和ART对口腔健康状况的长期影响，特别是在一些PLHIV的牙齿表面。需要进一步评估，以确定这是一个孤立的病例，还是撒哈拉以南非洲接受长期抗逆转录病毒治疗的艾滋病毒阳性成年患者中的常见结果。从这些研究中获得的信息将确定艾滋病毒感染者龋齿的严重程度，并指导制定适当的口腔保健指南，以管理艾滋病毒感染者。
BackgroundThe estimated number of people living with human immunodeficiency virus (HIV) (PLHIV) in Uganda is 1.5 million (7.3%). As of June 2016, 60% (898,197) of PLHIV were enrolled and receiving antiretroviral therapy (ART). In scientific literature, the effect of HIV and ART on dental caries remains equivocal. At the Prosthetics Clinic of the Department of Dentistry, Makerere University College of Health Sciences, we have seen a number of PLHIV who require replacement of missing teeth with partial or complete dentures as a result of extensive caries. Here we report a case of an HIV positive female patient with extensive dental caries resulting in complete edentulous jaws, associated with psychological stress and stigmatization.Case presentationA 52-year-old patient, HIV positive for fourteen (14) years and receiving antiretroviral therapy (ART) for the last four years wanted to replace her missing teeth for effective feeding and cosmetic reasons. A diagnosis of partially edentulous maxillary and mandibular arches, cervical caries of tooth # 12, 15, 25, 34 and retained roots of tooth # 11, 13, 22 and 35 was made. Following oral health education and mouth preparation, this patient received a set of removable acrylic full upper and lower dentures.ConclusionThis case may represent the long-term effects of HIV and ART on oral health status especially tooth surfaces in some PLHIV. Further evaluation is required to ascertain if this was an isolated case or it is a common finding among HIV positive adult patients receiving long-term ART in sub-Saharan Africa. Information emerging from these studies would establish the magnitude of dental caries among PLHIV and guide the development of appropriate oral health care guidelines in the management of people living with HIV.