Does the DASH diet lower blood pressure by altering peripheral vascular function?
Does the DASH diet lower blood pressure by altering peripheral vascular function?
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DOI：
10.1038/jhh.2009.65
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发表时间：
2010-05-01
影响因子：
2.7
通讯作者：
Frayn, K. N.
中科院分区：
文献类型：
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作者：
Hodson, L.;Harnden, K. E.;Frayn, K. N.
我们测试了控制高血压饮食(DASH)饮食中血压(BP)的降低是否与外周血管功能的改变有关：血管内皮功能(通过血流介导的肱动脉血管扩张(FMD)评估)和皮下脂肪组织血流量(ATBF)。我们还评估了心率变异性(HRV)的影响，作为衡量心脏自主控制的指标。我们将27名男性和女性分配给快速节食组和对照组。分别于空腹、摄入75g葡萄糖后、饮食干预前、后30d测定FMD、ATBF和HRV，以维持体重为目的。对照组不改变饮食，DASH饮食组的收缩压显著降低(P
We tested whether lowering of blood pressure (BP) on the dietary approaches to stop hypertension (DASH) diet was associated with changes in peripheral vascular function: endothelial function, assessed by flow-mediated vasodilatation (FMD) of the brachial artery, and subcutaneous adipose tissue blood flow (ATBF). We also assessed effects on heart rate variability (HRV) as a measure of autonomic control of the heart. We allocated 27 men and women to DASH diet and control groups. We measured FMD, ATBF and HRV on fasting and after ingestion of 75 g glucose, before and after 30 days on dietary intervention, aiming for weight maintenance. The control group did not change their diet.The DASH-diet group complied with the diet as shown by significant reductions in systolic (P