Saccular aneurysms on straight and curved vessels are subject to different hemodynamics: implications of intravascular stenting.
Saccular aneurysms on straight and curved vessels are subject to different hemodynamics: implications of intravascular stenting.
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发表时间：
2006-10
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通讯作者：
Hui Meng;Zhijie Wang;Minsuok Kim;Robert D. Ecker;L. Hopkins
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作者：
Hui Meng;Zhijie Wang;Minsuok Kim;Robert D. Ecker;L. Hopkins
我们的目的是研究犬静脉袋（侧壁或直血管）和兔弹性蛋白酶（弯曲血管）动脉瘤模型中血管内支架植入术的血流动力学影响。通过计算流体动力学模拟和体外流动可视化研究了支架（Wallstent）和非支架版本中的流动动力学，重点关注支架放置对血管内流动停滞和流动冲击的影响。结果表明，侧壁和弯曲动脉瘤模型具有根本不同的血流动力学（剪切驱动与惯性驱动），因此支架置入结局也不同。
Our aim was to examine hemodynamic implications of intravascular stenting in the canine venous pouch (sidewall or straight-vessel) and rabbit elastase (curved-vessel) aneurysm models. Flow dynamics in stented (Wallstent) and nonstented versions were studied by using computational fluid dynamics simulations and in vitro flow visualization, with a focus on stent placement effects on aneurysmal flow stagnancy and flow impingement. Results show that sidewall and curved aneurysm models have fundamentally different hemodynamics (shear-driven versus inertia-driven) and thus stent placement outcomes.