Colorectal cancer screening: An updated review of the available options.
Colorectal cancer screening: An updated review of the available options.
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DOI：
10.3748/wjg.v23.i28.5086
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发表时间：
2017-07-28
影响因子：
4.3
通讯作者：
Noureddine M
中科院分区：
文献类型：
--
作者：
Issa IA;Noureddine M
结直肠癌（CRC）是世界范围内发病率和死亡率的重要原因。然而，在过去十年中，由于采用了有效的筛查方案，结肠癌的发病率和死亡率正在下降。然而，在世界某些地区，CRC的发病率和死亡率仍在上升，可能是由于“西方化”的饮食、生活方式以及缺乏保健基础设施和资源等因素。参与和坚持不同的国家筛查计划仍然是限制筛查目标实现的障碍。从基于粪便的检查到具有不同敏感性和特异性的放射学和内窥镜检查，可采用不同的方法。然而，这些测试的可用性仅限于经济资源丰富的地区。最近，FDA批准了一种用于CRC筛查的血液检测（Epi procolon®）。这种基于血液的测试可能有助于增加参与和依从率。因此，增加了结肠癌的检测和预防。本文将讨论各种CRC筛查测试，特别关注有关新批准的血液测试的数据。最后，我们将提出一种简单的具有成本效益的CRC筛查程序算法。
Colorectal cancer (CRC) is a significant cause of morbidity and mortality worldwide. However, colon cancer incidence and mortality is declining over the past decade owing to adoption of effective screening programs. Nevertheless, in some parts of the world, CRC incidence and mortality remain on the rise, likely due to factors including “westernized” diet, lifestyle, and lack of health-care infrastructure and resources. Participation and adherence to different national screening programs remain obstacles limiting the achievement of screening goals. Different modalities are available ranging from stool based tests to radiology and endoscopy with varying sensitivity and specificity. However, the availability of these tests is limited to areas with high economic resources. Recently, FDA approved a blood-based test (Epi procolon®) for CRC screening. This blood based test may serve to increase the participation and adherence rates. Hence, leading to increase in colon cancer detection and prevention. This article will discuss various CRC screening tests with a particular focus on the data regarding the new approved blood test. Finally, we will propose an algorithm for a simple cost-effective CRC screening program.
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影响因子：
39
作者：
Bretthauer M;Kaminski MF;Løberg M;Zauber AG;Regula J;Kuipers EJ;Hernán MA;McFadden E;Sunde A;Kalager M;Dekker E;Lansdorp-Vogelaar I;Garborg K;Rupinski M;Spaander MC;Bugajski M;Høie O;Stefansson T;Hoff G;Adami HO;Nordic-European Initiative on Colorectal Cancer (NordICC) Study Group
通讯作者：
Nordic-European Initiative on Colorectal Cancer (NordICC) Study Group
DOI：
10.1016/s1052-5157(03)00054-0
发表时间：
2002-01-01
影响因子：
--
作者：
Bond, John H
通讯作者：
Bond, John H
影响因子：
10.3
作者：
Allison, James E.;Sakoda, Lori C.;Selby, Joseph V.
通讯作者：
Selby, Joseph V.
影响因子：
19.7
作者：
Burling, D;Halligan, S;Taylor, SA
通讯作者：
Taylor, SA
影响因子：
24.5
作者：
Church TR;Wandell M;Lofton-Day C;Mongin SJ;Burger M;Payne SR;Castaños-Vélez E;Blumenstein BA;Rösch T;Osborn N;Snover D;Day RW;Ransohoff DF;PRESEPT Clinical Study Steering Committee, Investigators and Study Team
通讯作者：
PRESEPT Clinical Study Steering Committee, Investigators and Study Team