What counters antibiotic resistance in nature?

What counters antibiotic resistance in nature?
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DOI:
10.1038/nchembio.745
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发表时间:
2012-01-01
影响因子:
14.8
通讯作者:
Kishony, Roy
Kishony, Roy
中科院分区:
生物学1区
文献类型:
--
作者:
Chait, Remy;Vetsigian, Kalin;Kishony, Roy

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抗生素在临床上会促进耐药性的传播,但在自然环境中可能存在各种机制,使天平向抗生素敏感性倾斜。研究这些机制可以帮助我们了解野生环境中耐药性和敏感性的进化动态,这可能会启发新的治疗策略。
Antibiotics promote the spread of resistance in the clinic, but various mechanisms may exist in natural environments that tilt the balance toward antibiotic sensitivity. Studying such mechanisms could help us understand the evolutionary dynamics of resistance and sensitivity in the wild, which may inspire new therapeutic strategies.