An anthropomorphic phantom study of the accuracy of CyberKnife spinal radiosurgery
An anthropomorphic phantom study of the accuracy of CyberKnife spinal radiosurgery
复制标题
DOI：
10.1227/01.neu.0000141080.54647.11
复制
发表时间：
2004-11-01
期刊：
影响因子：
4.8
通讯作者：
Wang, MY
中科院分区：
文献类型：
--
作者：
Cheng, Y;Main, W;Wang, MY
目的：立体定向放射外科--CyberKnife放射外科系统(Accuray，Inc.，Sunnyvale，CA)使用植入的不锈钢基准，在定位脊柱旁病变时需要最高的目标识别和定位准确度。本研究的目的是评估这种方法的临床相关准确性的总体系统。方法：CyberKnife的临床相关准确性取决于1)光束传输的准确性，这反过来代表了机器人和相机图像跟踪误差的汇编，以及2)源于计算机断层成像和治疗计划的靶点定位的内在准确性。在三个不同的CyberKnife设备上使用装载有放射变色胶片的头部和躯干模型来测量临床相关的准确性，并将其表示为治疗计划中剂量等值线的位移。结果：在三个不同的CyberKnife设备上测量的平均临床相关误差被确定为0.7+/-0.3 mm；这一结节不随计算机断层扫描而变化，层厚在0.625-1.5 mm范围内。平均治疗效果。测量精度为0.3+/-0.1 mm。径向平移至14 mm时，基准跟踪误差小于0.3 mm，旋转至4.5°时，基准跟踪误差小于0.7 mm。结论：对于以基准跟踪为靶点的相对静止脊柱病变的治疗，CyberKnife系统具有亚毫米精度。
OBJECTIVE: Stereotactic radiosurgery-requires the highest degree of accuracy in target identification and localization When targeting paraspinal lesions, the CyberKnife radiosurgical, system (Accuray, Inc., Sunnyvale, CA) uses implanted stainless steel fiducials. The purpose of this study was to, evaluate the total system ford clinically relevant accuracy of this approach.METHODS: The clinically relevant accuracy of the CyberKnife, depends on 1) the accuracy of beam delivery, which in turn-represents a compilation of robot and camera image-tracking errors, and 2) the inherent accuracy of target localization that stems,from,computed tomographic imaging and treatment planning. The clinically relevant accuracy was measured at three different CyberKnife facilities using head and torso phantoms loaded-with packs of radiochromic film and expressed as a displacement of the dose contours from the treatment planning.,RESULTS: The mean clinically, relevant error, as measured at three different CyberKnife facilities, was determined to be 0.7 +/- 0.3 mm; which did knot vary with computed tomographic, slice thickness in a range of 0.625 to 1.5 mm. The average treatment delivery. precision was 0.3 +/- 0.1 mm. Fiducial tracking error was less than 0.3 mm for radial translations up to 14 mm and less than 0.7 mm for rotations up to 4.5 degrees.CONCLUSION: For the treatment of relatively stationary spinal lesions targeted with fiducial tracking, the CyberKnife system is capable of submillimeter accuracy.