CT attenuation of paired HRCT scans obtained at full inspiratory/expiratory position: comparison with pulmonary function tests
CT attenuation of paired HRCT scans obtained at full inspiratory/expiratory position: comparison with pulmonary function tests
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DOI：
10.1007/s00330-002-1514-z
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发表时间：
2002-11-01
影响因子：
5.9
通讯作者：
Thelen, M
中科院分区：
文献类型：
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作者：
Kauczor, HU;Hast, J;Thelen, M
这项前瞻性研究的目的是测量在完全吸气/呼气位置获得的配对HRCT上的肺衰减，与肺功能检查（PFT）相关，并表征不同类型的呼吸功能损害。155例有或无肺部疾病的患者在全吸气/呼气位置进行配对HRCT。使用专用软件通过密度和面积测量法评价三个扫描对。PFT可用于所有患者的相关性（平均间隔5天）。全吸气时的平均肺密度（MLD）为-813 HU，全呼气时的MLD为-736 HU;两者以及呼气衰减增加均与静态和动态肺容量显著相关：高达r=0.68，p
The purpose of this prospective study was to measure lung attenuation at paired HRCT obtained at full inspiratory/expiratory position, to correlate with pulmonary function tests (PFTs) and to characterize different types of ventilatory impairment. One hundred fifty-five patients with and without pulmonary disease underwent paired HRCT obtained at full inspiratory/expiratory position. Three scan pairs were evaluated by densito- and planimetry using dedicated software. The PFTs were available for correlation in all patients (mean interval 5 days). Mean lung density (MLD) at full inspiration was -813 HU, and MLD at full expiration was -736 HU; both, as well as the expiratory attenuation increase, demonstrated significant correlations with static and dynamic lung volumes: up to r=0.68, p